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The time of disintegration is basically based by the pharmaceuticals keeping in mind the timing of the digestive system so that the medicine is administered at the correct location,throat, stomach,upper or lower intestines etc. to have the necessary effect.
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∙ 13y ago
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What is the disintegration time of film coated tablet?
30 mins
Are all Erythromycin tablets enteric coated?
The brand name Flagyl, which is non-generic Metronidazole, does offer an enteric coated option. Since I have used this medication more than on one occasion to treat giardiasis, I understand the severity of nausea that normally accompanies it's use as a side effect. While not entirely mitigating these symptoms, the enteric version does reduce them to a more tolerable level and make it more likely that patients will take their medication on time and to completion. For giardiasis, the enteric version of Flagyl should be the default prescription.
What is disintegration time of tablet?
dissintigration time is the time that required to convert solid tablet in to granlues.
Can a enteric coated aspirin be crushed?
While an enteric aspirin can be crushed it is not recommended. Enteric coated aspirin is usually time release. Crushing time release aspirin can cause one to overdose as the aspirin is released into the system all at once.
What is a disintegration time apparatus?
For a drug to show maximum availability in the body it must be in solution form. So as a first step, the tablets that we take in, should break down to smaller particles or granules.This breaking up process is known as disintegration. disintegration is an important parameter of the tablet. It is determined with an apparatus described
Can you crush tablets?
Some, yes. Others are coated for time release or safety. Ask your doctor or pharmacist for specific information.
What are the 4 categories of tablets that should never be crushed and explain why?
THERE ARE BASICALLY THREE GROUPS OF medications that should never be crushed, cut in half, or chewed: ENTERIC COATED-they are coated to disslove in the intestine, otherwise it can cause gastric irritation. TIME-RELEASE CAPSULES (also called spansules) -they are meant to be released over time, otherwise it can cause an overdose. SUSTAINED-RELEASE TABLETS- they are meant to be released over time, otherwise it can cause an overdose. Some common 2 letter abbreviations after the name of the medication to indicated time-relaease or sustained release::LA (long acting); DR (delayed release); SA (slow acting); SR (sustained release); ER (extended release).Read labels CAREFULLY.
What is the difference between Tylenol tablets and geltabs?
The geltabs are tablets which are coated with a smooth gelatin coating, (supposedly) making them easier to swallow than the plain kind.
What is the difference between enteric coated pellets and sr pellets?
Enteric coated tablet are only to make the medication easier on the stomach. The coating all comes off at about the same time in the body and the entire dose is absorbed. SR, CR, slow-release, controlled release, are manufactured to release the dose of medication slowly over usually 12 hours. They are not for the protection of the stomach but to allow once or twice a day dosing of medications. If a SR/CR is crushed or chewed before swallowing, the entire dose will be absorbed at once and could be very dangerous resulting in overdose.
What effect does crushing Dexedrine sr spanules have on potency efficiency and bioavailability of the active drug?
Enteric-coated drugs (time released/ sustained release capsules) don't disintegrate in the stomach b/c they are protected by the stomach acid. This drug has to reach an alkaline (non-acidic) environment (which is the small intestine) in order to disintegrate and get into the blood stream. Enteric coated tablets can remain in the stomach for a long time b/c they are protected from the acidic environment. Crushing dexedrine SR (beaded) capsules would alter the place and time of absorption of the drug so it wouldn't be able to provide the correct therapeutic effects. The rapid absorption of the drug would increase the bioavailability of the drug and would cause an increase in drug concentration. Drug toxicity could result. With the SR tablet it is slowly absorbed and limits the bioavailability of the drug, decreasing the drug serum concentration. -nursing student/ ADD patient and Dexedrine prescribed for 15 yrs.
What type of medication should never be crushed?
As a general rule, any medication that is in an Extended Release form should not be crushed. These may be labeled as XR, ER, XL, TR, or using other acronyms. Enteric coated Aspirin, while not labeled as extended release, is coated to provide protection against ulcers. Crushing these tablets will stop this protection. You must consult with your doctor before crushing any tablets.
What is the Difference bewtwwen Depakote ER and Depakote DR?
Depakote EC is enteric coated Depakote, which must be taken in multiple doses daily. Depakote ER is extended release Depakote, which can be taken once daily, and usually requires a dose increase of 8-20% compared with Depakote EC.
