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What is iVDPV?

Updated: 11/4/2022
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13y ago

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iVDPV= infective vaccine derived poliovirus

cVDPV= circulating vaccine derived poliovirus

aVDPV= ambiguous vaccine derived poliovirus

They are caused by a mutation regaining virulence in the attenuated poliovirus strains (Sabin 1-3) used for the oral poliomyelitis vaccine (OPV). Not sure of the specific difference between regressed strains though.

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13y ago
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