What is the best way to drive from Myrtle Beach SC to Indianapolis IN?

Answer 1

745 mi - about 12 hours 45 mins driving time.

Myrtle Beach, SC, USA to Indianapolis, IN, USA.

1. Head northeast on US-17 BUS N toward 5th Ave N 0.4 mi

2. Make a U-turn at 9th Ave N 135 ft

3. Slight right at Main St/US-501 N

Continue to follow US-501 N 43.6 mi

4. Merge onto US-501 N via the ramp to Dillon/Bennettsville 12.9 mi

5. Continue onto S Carolina 38 W 28.3 mi

6. Continue onto Broad St 0.6 mi

7. Turn left at W Main St/Shopping Center 385 0.1 mi

8. Take the 2nd right onto Cheraw St 0.6 mi

9. Slight right at Hamlet Hwy 2.1 mi

10. Continue onto S Carolina 38 W

Entering North Carolina 14.5 mi

11. Turn left to merge onto I-74 W/US-74 W toward Rockingham 7.6 mi

12. Take exit 311 for US-1 toward Rockingham/Southern Pines/Cheraw/US-220 0.3 mi

13. Turn right at US-1 N 2.0 mi

14. Turn left at W Broad Ave 0.4 mi

15. Turn right at US-220 N 26.9 mi

16. Continue onto I-73 N 50.6 mi

17. Continue onto US-220 N 2.0 mi

18. Take exit 81 to merge onto I-40 W toward Winston-Salem 12.2 mi

19. Continue onto US-421 N 12.7 mi

20. Take exit 6B for US-52 N/US-311 N/Notrth Carolina 8 N toward Mt Alry/Smith Reynolds/Airport 0.3 mi

21. Merge onto US-311 N/US-52 N

Continue to follow US-52 N 31.0 mi

22. Slight left at I-74 W 12.5 mi

23. Merge onto I-77 N

Partial toll road

Passing through Virginia

Entering West Virginia 172 mi

24. Slight left at I-64 W 17.8 mi

25. Take exit 40 to merge onto US-35 N/US-35 W toward Winfield/Point Pleasant

Continue to follow US-35 W

Entering Ohio 161 mi

26. Exit onto US-35 W toward Dayton 13.6 mi

27. Take the exit onto I-75 N toward Toledo 8.3 mi

28. Take exit 61 to merge onto I-70 W toward Indianapolis

Entering Indiana 107 mi

29. Take exit 83A for Ohio St 1.5 mi

30. Continue straight onto E Ohio St 0.6 mi

31. Turn left at N Pennsylvania St 0.2 mi

Indianapolis, IN, USA.