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The oesophagus is the first part of the alimentary tract after the oropharynx. The cardio-oesophageal junction is the point where the oesophagus meets the stomach (at it's cardiac end - meaning the part of the stomach closer to the heart), where there is a circumferential thickening of the muscles in the wall of the gastrointestinal tract (tube). This extra thickening in the muscle layer is called the cardio-oesophageal sphincter. When food swallowed reaches this part, the sphincter dilates (expands/opens) to allow food to pass through from the oesophagus to the stomach. Once the food passes, the sphincter contracts (narrows/closes down) to prevent the contents of the stomach from returning back to the oesophagus.

Regurgitation of stomach contents and resultant vomiting occurs when the functioning of this sphincter becomes defective.

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Q: What is the cardioesophageal sphincter?
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