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Tramadol is an agonist-antagonist and morphine is a full agonist. I know it probably makes no sense to you, but, ill try to explain the best i can. Many years ago Drug companies wanted to make a pill that killed pain without the euphoria and addiction potential. They made a few that are still on the market today, such as Tramadol, Nubain and 2 others i can't think of off-hand. Opiates work by attaching to opiate receptors in our brain. Agonists attach and let go giving you the high and pain killing effects we all know. There are many different types of opiate receptors in the brain and its thought that if scientists can find one to bind to the correct receptor we will have our magic pain pill. Tramadol, however is associated with addiction and euphoria and, sometimes more so dysphoria. I hope this was understandable and answers your ?.

BTW, morphine is a natural chemical extracted from the poppy plant and tramadol is synthetic.

Once again, i am not a pharmacist, nor do i have any pharmacological training, so, be careful out there!

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Q: What is the difference between tram idol and morphine?
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