Diels-Alder
Acetic anhydride and aniline are the reactants for the preparation of acetaanilide.
The chemical reaction is:C6H5NH2 + (CH3CO)2O → C6H5NHCOCH3 + CH3COOH
An acid anhydride is an organic compound that has two acyl groups bound to the same oxygen atom. Usually, the acyl groups come from the same caboxylic acid, he formula for the anhydride being (RC(O))2O + H2O
Acetic anhydride is a liquid at room temperature. It is a colorless, corrosive liquid with a pungent vinegar-like odor. It is commonly used in organic synthesis reactions.
Acetic anhydride is a restricted substance because it is a key precursor chemical used in the illegal production of heroin. Its control is necessary to prevent its misuse in the synthesis of illicit drugs.
Acetic anhydride and aniline are the reactants for the preparation of acetaanilide.
The main impurties are probably the unreacted reactants. i.e salicylic acid and some acetic anhydride (ethanoic anhydride)
The product of the reaction between anthracene and maleic anhydride is known as anthracene-maleic anhydride adduct. This adduct is commonly used in the synthesis of dyes, polymers, and other organic compounds.
The reaction is: (CH3CO)2O + H2O = 2 CH3COOH
Synthesis of acetyl chloride via the reaction of acetic acid with sulphuric acid
Melanin Synthesis
The chemical reaction is:C6H5NH2 + (CH3CO)2O → C6H5NHCOCH3 + CH3COOH
Aspirin is generally produced by the following mechanism (starting from basic materials) Phenol --(NaOH, CO2, heat)--> Sodium Salicylate (+para isomer) --(H2SO4)--> Salicylic acid --(acetic anhydride)--> acetylsalicylic acid (Aspirin) Due to the myriad of organic reactions, there are multiple possibilities at each stage. However, the above is the most efficient and common way of synthesizing Aspirin. For example, the last reaction (esterification) may be accomplished by using an acyl halide instead of an anhydride (e.g. ethanoyl/acetic chloride instead of acetic anhydride). However, the acyl halide is more costly to synthesize and more unstable to handle.
a prostaglandin (PGE2) synthesis inhibitor
Jacob Meyer Zeavin has written: 'Preparation of some monoderivatives of benzoic anhydride and their reaction with Friedel-Crafts' synthesis'
The product of the reaction between 4-aminophenol and excess acetic anhydride is acetaminophen, also known as paracetamol. This reaction is a nucleophilic acyl substitution reaction that forms an amide functional group on the 4-aminophenol molecule.
The synthesis of E and Z α-phenylcinnamic acid can be achieved through the Wittig reaction, which involves the reaction of an aldehyde or ketone with a phosphonium ylide to form an alkene. By selecting appropriate reactants with specific stereochemistry, either the E or Z isomer can be obtained. Moreover, the stereochemistry of the product can be controlled by the choice of the phosphonium ylide used in the reaction.