autosomal recessive
Sickle Cell Anaemia is a single gene defect (Hb gene).
The condition is called sickle cell trait. This occurs when an individual inherits one sickle cell gene and one normal hemoglobin gene, resulting in milder symptoms compared to sickle cell disease.
A child has to receive the gene from both parents to heve sickle cell anemia. if only one parent passes on the gene, then the child will have sickle cell trait, but no symptoms of sickle cell anemia.
People who inherit one sickle cell gene are said to have sickle cell trait. This means they carry the gene but do not typically have symptoms of sickle cell disease. It is important for individuals with sickle cell trait to be aware of their status for proper medical management and genetic counseling.
If you carry the sickle cell gene, it doesn't really mean much as far as your own personal health goes. Except that you are less likely to get malaria. However, if you decide to have kids, and whoever you mate with also carries the sickle cell gene (not the full blown disease/gene) , your child has a chance of having sickle cell disease (full blown).
If one represents a sickle cell gene thus "C" and a normal gene thus "O" then both parents are: Mum CO Dad CO The possibilities for their children are therefore CC OO CO CO in those proportion so 1in 4 will have sickle cell anaemia, 2 in 4 will be carriers (like their parents) and 1/4 will be normal.
No, it's not a one gene disorder
No, sickle cell anemia and sickle cell trait are not the same. Sickle cell anemia is a severe form of the disease caused by inheriting two sickle cell genes (one from each parent), leading to significant health complications. In contrast, sickle cell trait occurs when an individual inherits only one sickle cell gene and one normal gene, typically resulting in no symptoms but allowing the person to pass the trait to their offspring.
The person is homozygous for the trait
you dont have to worry about getting sickle cell if your not african american
rr since sickle cell is a recessive trait.
A person with one sickle cell gene and one normal hemoglobin gene has sickle cell trait, which can provide some protection against malaria. This advantage makes them more capable of surviving in regions where malaria is prevalent compared to someone with no sickle cell genes, who would be more susceptible to severe malaria infection.