You can never say whats the most powerful weapon is.
It's an opinion, and different weapons are used for different things.
If you say p-90 for example it might be that one week later a grenade thrower is the most powerfull weapon cause they are developing new weapons all the time so that's it.
ADDED: I somewhat agree with the premise of the first answer but I would exclude weapons such as grenade and RPG launchers, and limit the answer only to firearms capable of being handheld (i.e.- handguns and rifles.) The handgun would chamber the: .454 Casull - the rifle would be the 50 caliber.
There are hand guns that chamber rounds more powerful than the .454
ADDED: The above are correct but mention cartridges. For the sake of the question I shall add that most powerful mass produced firearm would be the Barret's semi automatic rifle in caliber .50BMG. There are other manufacturers who do make clones of this firearm.
It is the same power as any other firearm that is firing the same caliber cartridge. Contrary to myth, this is NOT the most powerful handgun in the world- not even close.
The Russian mafia is the 2nd most powerful mafia in todays world. The Italian mafia is the most powerful mafia in the world
22 rifle
Power (within limits) is not a function of the firearm, but of the cartridge fired by that firearm. A 9mm submachinegun is as powerful as another 9mm submachinegun, a .45 as powerful as a .45, etc.
The president isn't the most powerful person in the world. God is. Presidents are the most powerful and important people in the USA.
the most powerful telescope in the world is the lbt
No, there are more powerful militaries in the world.
After the first world war the USA became the most powerful one.
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loyalty is the scond most powerful thing in the world.
The World's fastest, most powerful and the most expensive combat aircraft is the F-22 stealth raptor.