The conjugate acid is Hydrogen (H2), the pKa of which is 35.
The pKa of sulfonic acid is < 0
From this salt the benzoate ion C6H5-COO- is a base ( the other part Na+ is neutral).This base has a pKB value of 9.80 (benzoate)The pKacid value of its conjugated benzoic acid ( C6H5-COOH) however ispKbenzoic-acid = 4.20 = pKa(which is (not surprisingly) equal to 14.0-pKbase = 14.0-9.80)
The effective range should be the pKa +/- 1. Therefore, the range should be 1.15 to 3.15.
The pKa of HSO4- (the second pKa of H2SO4) is 1.92. The Ka is thus 0.0120
Doxofylline Pka value is about 9.8.
pKa = 15
It is around pKa=13
By following + or - 2 pH to the pKa value
The pka of a protonated ether (the conjugate acid) is about -3.5
The conjugate acid is Hydrogen (H2), the pKa of which is 35.
7.6
if Pka value is more for acidic drug,best side for absorption will be throughout the G.i.Tract.
pKa = 6.36 of carbonic acid to HCO3-
actual pka of betaxolol is 9.4 but observed is 9.38
The pKa of sulfonic acid is < 0
A pKa value is a measurement used for bases and acids. The measurement pH applies to hydronium ion concentrations that are in a solution, whereas pKa only applies to determining the amount of dissociation an acid wants to do in a solution.