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Q: What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?
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Why do platelets initialy stick to the wall of a damaged blood vessel?

Well, platelets create a micro fibril when they come in contact with the ruptured vein/capillary walls, this fibril is i guess you can say sticky, from there they build up and create a mesh that in time creates a scab so no more blood is lost.


A platelet plug begins to form when platelets are?

exposed to a rough surface


What are the three processes for platelet plug formation?

Here are the three processes for platelet plug formation:1. Platelet adhesionThe platelets will adhere to the collage fibres exposed in a damaged blood vessel. This occurs when the glycoprotein 1b (GPb1) receptors of the platelets interact with the von Willebrand factor (vWb) synthesised by endothelium.2. Platelet activationThis process is initiated by the collagen fibres, the adenosine diphosphate (ADP), and thrombin. It causes the platelets to synthesise thromboxane A2 (TXA2) and to releasethe contents of their dense granules which contain ADP and 5-hydroxytryptamine.3. Platelet aggregationThe released mediators will cause the platelets to change from a discoid shape to a sphere with spiny projections. This new shape will increase the chances of the platelets making contact with other platelets. The platelets will then aggregate with fibrinogen and vWf as connecting agents via their glycoprotein IIb/IIIa receptors. ADP and TXA2 act as chemotactic factors to attract more platelets and the positive feedback loop created forms the platelet plug which temporarily seals the break in the damaged blood vessel.


How blood clotting prevent inside human body?

Normally the beginning of a blood clot, platelet plug formation, doesn't occur unless the platelets are exposed to the underlying collagen fibers. That doesn't happen unless the blood vessel has been damaged so clots usually only occur in response to a damaged blood vessel.


What are the causes of thrombophlebitis?

The main causes can be grouped into three categories; injury to blood veins, increased blood clotting, and blood stasis. When blood veins are damaged, collagen in the blood vein wall is exposed. Platelets respond to collagen by.


What are the major components of haemostatic mechanism?

These are the 3 components of haemostasis:Step 1: Vascular spasmThe smooth muscle of the blood vessel contracts resulting in vasoconstrictionStep 2: Platelet plug formationThe injury of the lining of the blood vessel exposes its collagen fibers. The platelets will adhere to these exposed fibers.Step 3: CoagulationThe fibrin forms a mesh trapping red blood cells and platelets. This leads to the formation of the clot.


What causes thrombocytopenia hallucinations and hypothermia?

Hypothermia is caused by being exposed to cold temperatures for too long. Thrombocytopenia hallucinations are caused by a low blood platelet count.


What would happen to people exposed to a chemical warfare agent that blocked acetylcholine from binding to muscle receptors?

Muscle contractions would be prevented, causing paralysis.


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The retinal receptors in the eye, called cones, are what sense colors.Three things must be present to see colour:1. Light2. An exposed retina3. Consciousness


How can you see color?

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How does the human body close a cut?

our blood has substances called as blood platelets. When blood is exposed to air, the platelets solidify and thus the blood from a cut gets stopped. Having low platelet count in the blood can be fatal even if you have a small wound...


What type of proteins do the white blood cells look for in cell identification?

They look for pathogen specific or pathogen associated proteins presented by MHC molecules. However the also need interactions by co-receptors. These co-receptors are only expressed it the cells are exposed to pathogen associated molecular paterns. Ermm, that might not be the best answer but I hope you get the idea...