Take the Uptown 1-2-3 (the red line), 1 stop, from 34th Street-Penn Station to 42nd Street-Times Square.
Transfer at Times Square to the Downtown N-R-Q (the yellow line), and take the Downtown N-R-Q to Canal Street (at Broadway). This station is located in the heart of Chinatown.
No, the AirTrain takes you to and from the subway, and the subway takes you to and from Penn Station. Take the AirTrain to the Howard Beach Station, and get the Manhattan-bound A train (of the A-C-E, the blue line) to 34th Street-Penn Station.
Take the Uptown E train (of the A-C-E, the blue line) from 34th Street-Penn Station to Court Square.
Yes, the 3 train stops at Penn Station. All trains on the 1-2-3 line (the red line) and the A-C-E line (the blue line) stop at Penn Station.However, the 3 does NOT stop at Penn Station from 11:30 PM to 6 AM. During those times, the line ends at 42nd Street-Times Square.
Take the Uptown 1-2-3 (the red line) from 34th Street-Penn Station to 42nd Street-Times Square, and transfer there to the N.
You don't have to take the subway; it's 2 blocks. Penn Station is at 34th Street between 8th and 7th Avenues, and 520 8th Avenue is between 36th and 37th Streets.
Take the Downtown 2 or 3 trains (of the 1-2-3, the red line) from 34th Street-Penn Station to Wall Street (at William Street).
Take the Uptown 1 train (of the 1-2-3, the red line) from 34th Street-Penn Station to 66th Street-Lincoln Center (at Broadway).
Take the Downtown 1 train (of the 1-2-3, the red line), 1 stop, from 34th Street-Penn Station to 28th Street (at 7th Avenue).
The A train (of the A-C-E, the blue line). Take the Downtown A train from 175th Street to 34th Street-Penn Station. Entrance to the 175th Street station is included inside the bus terminal complex.
You take the subway to New York City Penn Station. Then you get on a Northeastern Regional train going south to Philadelphia. Trains leave Penn Station regularly.
Walk west to Lexington Avenue and north to 53rd Street, and take the Downtown E train (of the A-C-E, the blue line) from Lexington Avenue-53rd Street to 34th Street-Penn Station.
The only Number 6 train you may be referring to is the MTA Subway number 6. This train line does not go to NYC Penn Station, but does go to Grand Central Station. The best suggestion is to take the MTA "S" train (for Shuttle) that gives you a very fast trip from Penn Station to Grand Central. There you will find the number 6 train.