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Unless there are big stickers saying otherwise, any vehicle will use ethelyne glycol based anti-freeze/boil-over protection coolant, such as Prestone, Prime, et cetera. Just beware of the 'really cheap' coolant, which is a 50/50 mix of coolant and water. Such is what you are supposed to add to the cooling system, but knowing how to drain the block is beyond most people, and, without draining the block, getting proper concentration in the cooling system using a 50/50 mix can be difficult. I recommend buying undiluted coolant, pouring out about a quart, and adding a quart of water to the jug, mixing well, and then adding to the cooling system. (Of course, this is after the cooling system has been properly back flushed to clean out sludge and corrosion.) Do not pour undiluted coolant into the cooling system, as it can corrode portions thereof before it mixes with the water in the cooling system. Do not run undiluted coolant in the cooling system, for the same reason. A 50/50 mix will protect a cooling system to about -45 degrees Fahrenheit, and if if gets colder than that where you live, you should be aware of the extra precautions you should take, such as block heaters, oil heaters, et cetera. It is necessary to have water in the cooling system for it to work properly, the anti-freeze is there to keep the water from freezing, not to act as a coolant on its own.

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Q: What type coolant is recommended by the manufacturer for a 2001 Buick Regal?
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