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Yes, causing an increasingly uncomfortable feeling of restlessness, agitation, and the need to move about constantly, often exhibited in such people. Some of them ignore it even then! The body is thus locked in a struggle with itself, and the mind refuses to give in and allow urination. Such people often require therapy.

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Q: When the urge to urinate is ignored does the sympathetic nervous system gradually become more aroused to oppose the micturition reflex arc?
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