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Around the Mediterranean Sea.

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Marley Williamson

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Q: Where is sickle cell allele most frequent?
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Where is the sickle-cell allele most frequent?

Around the mediterranean sea.


Where is the sickle cell allele most frequent?

Around the Mediterranean Sea.


What is the most frequent hemoglobin disease in the ambulatory care?

Anemia and thalacemia


How does a person with sickle-cell allele differ from a person with two sickle-cell alleles?

If a person has a single sickle cell allele they will have some sickles red blood cells, and some normal red blood cells. This is the origami purpose that this evolved for. If a person had a single sickle cell allele, they will be mostly resistant to malaria. This is why sickle cell anemia is most prevalent in areas of the world where malaria is common. However, if a person has two sickle cell anemia alleles, they will have ONLY sickled red blood cells. The "sickling" of the red blood cells is caused by a mutation in the protien that the gene codes for. That protein is hemoglobin, which carries oxygen through the blood. If a person has sickle cell anemia, parts of their body wil not get enough oxygen. They can pass out, loose sensation in the limb, or even die from it. In short, a person with two alleles is sick, and a person with one allele is not.


Is there any evidence that the traits shared by most of the population is not controlled by a dominant allele explain?

If the allele is beneficial then recessive alleles will drive to fixation in the population. Sickle cell trait is a fair example of this.


Who has a sickle cell trait?

No. Many people become confused with that because the Sickle Cell trait is most common in Africa where the population is more black than any other race.


What groups get sickle cell disease?

A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.


Is it safe for someone with sickle cell to have a baby?

AnswerAs you already must know Sickle Cell disease is genetic, but the GOOD NEWS is there is no known risk that babies may develop sickle cell disease.It's a good idea to first check with a genetic specialist and make your decision from there.Good luck!


Where in the world are the most cases of Malaria and Sickle Cell anaemia?

Malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.


In which area in Africa would you expect the sickle-cell hemoglobin gene to be the most common?

The area with the most malaria. Sickle-cell confers resistance against malaria, and so you'd expect populations in the most malaria heavy zones to have the highest prevalance of sickle-cell anemia.


When does sickle cell disease appear?

Most people develop symptoms of sickle cell disease in early childhood (4-9 months)


What are the most facts about sickle cell anemia?

Miles Davis, Paul Williams, Tionne, and Georgeanna Tillman are famous celebrities that have or had sickle cell disease.