Africa is a continent and contains many countries so to answer your question we need to know the area or country you want to know about.
Durban
Timbuktu is actually in Africa. It is a city in the country called Mali, which is in the northwest of Africa.
The closest city is Cape Town and the country is South Africa
Cairo, Egypt.
The city closest to this point is Durban, South Africa.
The Royal Bafokeng Stadium, near Rustenburg, South Africa - is the closest to Sun City
The closest major city to that point is Durban, South Africa.
Western Australia is closest to Africa.
Venezuela is the most closest to the size of Niger Africa
Quito is the closest major city and Banos is the closest town.
one of closest city is buchun.
The distance between South America and Africa at their closest is 2848 kilometers. The closest points are Touros, Brazil and Sherbro Island, Sierra Leone.