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William Clark and Meriwether Lewis explored and mapped the American west. Sacajawea, a Shoshone Indian guide and interpreter accompanied them part of the way. They traveled from Missouri to Oregon and back again, sometimes by river and sometimes by land. The 8,000-mile trip took a total of 2 years, 4 months, and 10 days.

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Q: Who led an exploration of the land west of the Mississippi River?
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