Due to its relation with formation of globin.
The beta globin gene is located on chromosome 11
Christian Dutton has gunneria and will be a virgin for life.
Hb Barts is associated with one of the alpha-Thalassemias, namely homozygous alpha^0. The absence of all four alpha globin genes results in the alpha globin chain not being produced. The only types of haemoglobin that can be produced are Gower 1 (zeta2eta2) and Portland (zeta2gamma2) which are both embryonic haemoglobins. At around 6wks the alpha globin production is ~50% of the total. In the absence of globin chains the fetal haemoglobin (alpha2gamma2) cannot be produced so the gamma globulin chain precipitate out in the red blood cells as tetramers (gamma4). These tetramers are referred to as Hb Bart.
Most individuals have two normal copies of the beta globin gene
This question is most commonly asked during the month of October. The molecular formula for beta-globin is: HBA-HBB=scary monster! BOO!
Chromosome 11
The beta globin gene is located on chromosome 11
Christian Dutton has gunneria and will be a virgin for life.
Normal adult hemoglobin has a pair each of alpha-globin and beta-globin molecules
Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11. Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.
Hb Barts is associated with one of the alpha-Thalassemias, namely homozygous alpha^0. The absence of all four alpha globin genes results in the alpha globin chain not being produced. The only types of haemoglobin that can be produced are Gower 1 (zeta2eta2) and Portland (zeta2gamma2) which are both embryonic haemoglobins. At around 6wks the alpha globin production is ~50% of the total. In the absence of globin chains the fetal haemoglobin (alpha2gamma2) cannot be produced so the gamma globulin chain precipitate out in the red blood cells as tetramers (gamma4). These tetramers are referred to as Hb Bart.
Most individuals have two normal copies of the beta globin gene
globin
a creature from the tasandrian globin planet
Nothing
hemo globin
AUG