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Water and lipids (fat) react differently in the body. The lipids are stored by the body and the water is absorbed into the body. Certain drugs and conditions may interfere with the ability to absorb them and to much of them can cause illness.
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Difference between lipid soluble drug and water soluble drug?
lipid soluable means that it disolves in fat, and water soluable means it disolves in water.
Why do mole drug molecules have both water-soluble and oil-soluble functional groups?
The drug has to be water soluble to dissolve as gastrointestinal fluid is aqueous. The drug also has to be oil soluble as only the lipid soluble non-ionized form can readily diffuse across the lipid membrane.
Explain the role of blood in transportation of a drug in a human body?
It depends on the drug and whether it is water or lipid soluble. Many drugs are bound and transported by plasma proteins.
Is Valium water or fat soluble?
According to the manufacturing company, Diazepam (Valium) is a highly lipid-soluble benzodiazepine. Diazepam remains a popular oral drug for preoperative medication of adults.
What section of a drug monograph would tell you if the drug is soluble water?
This section of a drug monograph would tell you if the drug is soluble in water.
What is the effect of body fat on lipid soluble drug elimination?
It slows it - the drug must leave the fat cells before it can be eliminated.
How might a polar medicine behave differently within your body than a nonpolar medicine would?
The compounds in medicine should be non polar. It is important for any drug to be able to dissolve itself through the cell membrane which consists of a lipid bi-layer, in order to diffuse in the body and circulate biologically, performing its function. Non polar compounds are lipid soluble and therefore can dissolve in the lipid layers. Polar compounds are water soluble and fail to cross the cell membrane. Therefore scientists need to be sure of using compounds that are non polar in nature so they pass through the cell membrane and enter into the blood circulation of the body and perform its due function.
Why are drugs in solid form unlikely to be absorbed in the stomach to any significant extent?
Only the lipid soluble non-ionized form of a drug can diffuse across the membrane. The pH is low in the stomach. For the acidic drugs, they are non-ionized at low pH yet they are poorly soluble. For the basic drugs, they are soluble yet ionized.
Can traces of molly drug be found in your blood?
Yes. MDMA is a water soluble drug, which means, it can stay in your blood and urine for up to 1-4 days
How do you dissolve sodium pentothal?
Sodium pentothal (thional) is soluble in water or ethanol.Take care, this drug may be dangerous.
Oral hypoglycemic drug affect lipid metabolism?
Metformin
Is bactrim a fat soluble drug?
yes
