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What is the P53 gene function?
p53 is a gene that codes for a protein (p53) that is an important tumor suppressor. Although the number of pathways and roles of p53 continue to expand it is, perhaps, most well known for slowing cell proliferation or inducing apoptosis if DNA damage or uncontrolled growth is detected.
What is the role of the transactiovation domain of p53?
p53 it ripari DNA demaged fragments.
What is p53 marker?
The p53 is the tumor suppressor protein that regulates cell cycles and hence has a role in preventing cancer.
What type of gene is the p53 gene?
p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressorthat is involved in preventing cancer. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation.The name p53 is in reference to its apparent molecular mass: It runs as a 53-kilodalton (kDa) protein on SDS-PAGE. But, based on calculations from its amino acid residues, p53's mass is actually only 43.7 kDa. This difference is due to the high number of prolineresidues in the protein, which slows its migration on SDS-PAGE, thus making it appear heavier than it actually is. This effect is observed with p53 from a variety of species, including humans, rodents, frogs, and fish..
What is P53 and what does it have to do with cancer?
The human gene known as p53 is a tumor suppressor gene and malfunctions of it have been implicated in many cancer types. Research is using it to study the biology of cancer, as well as to develop new drug targets to cure certain cancers.In 1993, p53 protein was named Molecule of the Year by Science magazine. It is a protein that is very important for the regulation of cell cycles in humans and other multi-cellular organisms. p53 is also known as TP53 and several other names including tumor protein (EC :2.7.1.37), the "guardian of the genome", and the "Guardian Angel Gene" (because it works to prevent mutation or damage to the genome).Most recent genetic research is also promising in the search for cancer causes and treatments. The research indicates there is a relationship between development of cancer and insufficiency of the p53 gene.More than 50% of the tumors in humans show a mutation of or deletion of this gene. It is believed that various things can cause the mutations or damage/deletion of p53, such as DNA damage from chemicals, UV ray damage, and there are some known viruses that can inhibit the function of p53, such as Simian Virus 40 (SV40) and Human Papillomavirus (HPV), an STD.These viruses and DNA damage can inactivate p53, rendering it ineffective for tumor suppression.See more in related questions and links.
What is the P53 gene function?
p53 is a gene that codes for a protein (p53) that is an important tumor suppressor. Although the number of pathways and roles of p53 continue to expand it is, perhaps, most well known for slowing cell proliferation or inducing apoptosis if DNA damage or uncontrolled growth is detected.
What is the role of the transactiovation domain of p53?
p53 it ripari DNA demaged fragments.
What has the author Gerard P Zambetti written?
Gerard P. Zambetti has written: 'The p53 tumor suppressor pathway and cancer' -- subject(s): P53 antioncogene, P53 protein
What is p53 marker?
The p53 is the tumor suppressor protein that regulates cell cycles and hence has a role in preventing cancer.
What cancers does the p53 cancer gene cause?
P53 it is an anzyme that monitorize the DNA and protect them from demagis.It is founded that its defective in 60% of cancer cells
A cell with a defective p53 gene is likely to?
A defective P53 gene is likely to cause poor regulation of cell cycles. P53 is a protein that suppresses tumor production and is implicated as a factor in cancer development. It prevents genome mutation and damage. 50% of human tumors have mutated or deleted P53 genes.
What is p53 called?
"The Guardian Angel Gene"
What is one factor that can cause the cycle to lose control?
Loss of cell cycle control is typically an oncogenic process. For cancer to occur, the cells need to replicate beyond any normal physiological control. To answer your question, one factor that in important in controlling the cell cycle is p53. p53 is a checkpoint control in the G1 phase of the cell cycle. Defects in p53 cause a loss of cell cycle regulation and are considered an oncogenic transformation.
What is one factor can cause the cell cycle to lose control?
Loss of cell cycle control is typically an oncogenic process. For cancer to occur, the cells need to replicate beyond any normal physiological control. To answer your question, one factor that in important in controlling the cell cycle is p53. p53 is a checkpoint control in the G1 phase of the cell cycle. Defects in p53 cause a loss of cell cycle regulation and are considered an oncogenic transformation.
What is one factor that can cause the cell to lose control?
Loss of cell cycle control is typically an oncogenic process. For cancer to occur, the cells need to replicate beyond any normal physiological control. To answer your question, one factor that in important in controlling the cell cycle is p53. p53 is a checkpoint control in the G1 phase of the cell cycle. Defects in p53 cause a loss of cell cycle regulation and are considered an oncogenic transformation.
What is one factor that can cause cells to lose control?
Loss of cell cycle control is typically an oncogenic process. For cancer to occur, the cells need to replicate beyond any normal physiological control. To answer your question, one factor that in important in controlling the cell cycle is p53. p53 is a checkpoint control in the G1 phase of the cell cycle. Defects in p53 cause a loss of cell cycle regulation and are considered an oncogenic transformation.
What is on factor that can cause the cell cycle to lose control?
Loss of cell cycle control is typically an oncogenic process. For cancer to occur, the cells need to replicate beyond any normal physiological control. To answer your question, one factor that in important in controlling the cell cycle is p53. p53 is a checkpoint control in the G1 phase of the cell cycle. Defects in p53 cause a loss of cell cycle regulation and are considered an oncogenic transformation.
