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Slightly permeable to sodium ions.
Potassium and sodium determine the a cell's resting membrane potential. The equilibrium potential (the voltage where no ion would flow) for sodium is about +60 mV while that for potassium is usually around -80 mV, but because the resting cell membrane is approximately 75 times more permeable to potassium than to sodium, the resting potential is closer the the equilibrium potential of potassium. This is because potassium leak channels are always open while sodium come in through voltage gated or ligand gated channels.
sodium/potassium pump
sodium-potassium
The resting potential is the normal equilibrium charge difference (potential gradient) across the neuronal membrane, created by the imbalance in sodium, potassium, and chloride ions inside and outside the neuron.
Slightly permeable to sodium ions.
Potassium and sodium determine the a cell's resting membrane potential. The equilibrium potential (the voltage where no ion would flow) for sodium is about +60 mV while that for potassium is usually around -80 mV, but because the resting cell membrane is approximately 75 times more permeable to potassium than to sodium, the resting potential is closer the the equilibrium potential of potassium. This is because potassium leak channels are always open while sodium come in through voltage gated or ligand gated channels.
sodium/potassium pump
sodium-potassium
The equilibrium potential refers to the electrochemical potential at equilibrium of a particular ion, as calculated by the Nernst equation. The resting potential refers to the weighted average based upon membrane permeabilities of all the equilibrium potentials of the various ions in a given cell, as calculated by the Goldman equation.
The resting membrane potential is the difference between the inside of the cell relative to the outside. The outside is always taken as 0mv. The resting membrane potential is negative because there is a higher concentration of potassium ions outside the cell (because the membrane is more permeable to potassium ions) than inside. Since potassium ions are positively charged this leads to a negative value.
A potassium enhanced intravenous solution would increase the concentration of potassium ions in the brain. Since potassium ions are positively charged, they depolarize the resting membrane potential. For example, a resting membrane potential of -65 millivolts would be depolarized to -62 millivolts. An appropriate concentration could lead to a significant depolarization of, say, -60 millivolts, at which point an action potential could be possible.
False
Sodium-potassium pump
The resting potential is the normal equilibrium charge difference (potential gradient) across the neuronal membrane, created by the imbalance in sodium, potassium, and chloride ions inside and outside the neuron.
It is -70 millivolts. The resting potential of a neuron refers to the voltage difference across the plasma membrane of the cell, and is expressed as the voltage inside the membrane relative to the voltage outside the membrane. The typical resting potential voltage for a neuron is -70mV Resting potentials occur because of the difference in concentration of ions inside and outside of the cell, largely by K+ (Potassium ions) but some contribution is made by Na+(Sodium ions)
The resting membrane potential of a typical neuron is around -65mV