Assuming the fuel filter has been changed, most commonly a bad fuel pump.
yes it would or it might be the starter
Under the upper intake manifold. The upper intake manifold would have to be removed to gain access to the bank of injector poppets (the spider).
That truck has two fuel injectors in the throttle body. I doubt that both are bad. I would suspect the fuel pump is faulty.
Yes
No, the injectors are rated differently, you would be dumping fuel into the engine. The computer and injectors wouldn't match up.
yes, 82-93 are the same besides grill design
the 1996 and 1997 are the same and would not work in your 2000 straight from GM
The rear brake on that side may be locking up and getting extremely hot.
That would be the 4L60E
That vehicle would have throttle body fuel injection in which case it would have two fuel injectors.
The Vortec Engines with the Spyder, or octopus type fuel injectors had issues with the clip on the fuel injector harness breaking. thus, causing it to come loose which would cause random misfires. also causes could be low compression, bad plugs and wires, dirty injectors, cattilytic converters.
Could be, in need of a tune up, vacuum leaks, leaky fuel injectors,