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Yes. Mice have a much higher metabolic rate than a cow does, which means a mouse has to eat more per body weight than a cow to keep it alive and able to move around. We have to look at how much a mouse and a cow drink on a per-body weight basis to see whether a mouse will or will not dehydrate faster than a cow will. We cannot compare how much a cow drinks or a mouse drinks per day in terms of gross volume, since these are unreliable numbers to work with. Thus, typically a mouse will drink 15% to 20% of its body weight in water per day. A cow, on the other hand, will drink 7 to 10% of her body weight in water per day. This is a huge difference, and shows that mice indeed will dehydrate faster than a cow will.

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