ABO incompatibility is a reaction of the immune system that occurs if two different and not compatible blood types are mixed together.
Causes, incidence, and risk factorsA, B, and O are the three major blood types. The types are based on small substances (molecules) on the surface of the blood cells. In people who have different blood types, these molecules act as immune system triggers (antigens).
Each person has a combination of two of these surface molecules. Type O lacks any molecule. The different blood types are:
People who have one blood type form proteins (antibodies) that cause their immune system to react against other blood types. Being exposed to another type of blood can cause a reaction. This is important when a patient needs to receive blood (transfusion) or have an organ transplant. The blood types must be matched to avoid an ABO incompatibility reaction.
For example:
Because type O lacks any surface molecules, type O blood does not cause an immune response. This is why type O blood cells can be given to patients of any blood type. People with type O blood are called "universal donors." However, people with type O can only receive type O blood.
Since antibodies are in the liquid part of blood (plasma), both blood and plasma transfusions must be matched to avoid an immune reaction.
SymptomsThe following are symptoms of transfusion reactions:
Signs and testsTreatment may include:
This can be a very serious problem which can even result in death. With the right treatment, a full recovery is likely.
ComplicationsCall your health care provider if you have recently had a blood transfusion or transplant and you have the symptoms listed above.
PreventionCareful testing of donor and patient blood types before transfusion or transplant can prevent this problem.
ReferencesMcPherson RA, Pincus MR. Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. Philadelphia, Pa: Saunders; 2006.
Hoffman R, Benz E, Shattil S, Furie B, Cohen H. Hematology: Basic Principles and Practice. 4th ed. Philadelphia, Pa: Churchill Livingstone; 2004.
ABO incompatibility is an immune system reaction that occurs when blood from two different and incompatible blood types are mixed together.
See also: Transfusion reaction - hemolytic
Causes, incidence, and risk factorsA, B, and O are the three major blood types. The types are based on small substances (molecules) on the surface of the blood cells. In people who have different blood types, these molecules act as immune system triggers (antigens).
Each person has a combination of two of these surface molecules. Type O lacks any molecule. The different blood types are:
People who have one blood type form proteins (antibodies) that cause their immune system to react against other blood types. Being exposed to another type of blood can cause a reaction. This is important when a patient needs to receive blood (transfusion) or have an organ transplant. The blood types must be matched to avoid an ABO incompatibility reaction.
For example:
Because type O does not have any surface molecules, type O blood does not cause an immune response based on ABO incompatibility. This is why type O blood cells can be given to patients of any blood type. People with type O blood are called "universal donors." However, people with type O can only receive type O blood.
Since antibodies are in the liquid part of blood (plasma), both blood and plasma transfusions must be matched to avoid an immune reaction.
SymptomsThe following are symptoms of ABO incompatible transfusion reactions:
Treatment may include:
ABO incompatibility can be a very serious problem that can even result in death. With the right treatment, a full recovery is likely.
ComplicationsCall your health care provider if you have recently had a blood transfusion or transplant and you have symptoms of ABO incompatibility.
PreventionCareful testing of donor and patient blood types before transfusion or transplant can prevent this problem.
ReferencesGoodnough L. Transfusion medicine. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 183.
Wu YY, Mantha S, Snyder EL. Transfusion reactions. In: Hoffman R, Benz E Jr, Shattil S, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone; 2008:chap 153.
Reviewed ByReview Date: 08/24/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
between ABO and Rh incompatibility
NISHOT statistics include mistransfusion and ABO/Rh-incompatibility.
To determine if the newborn has ABO incompatibility
Yes,but if the baby is blood type B then there is ABO incompatibility.
Well there is an ABO and Rh incompatibility, then baby is at risk of jaundice or erythroblastosis fetalis.
if O- mother consives A+ OR B- baby any foetal A or B TYPE RBC ENTERING THE MOTHERS blood cells are quickly distroyed by her anti-A or anti-B antibodies before she can form -Rh antibodies
The usual cause of abnormal hemolysis in newborn is blood group incompatibility between mother and baby either Rh or ABO. Other causes are much less common-hereditary spherocytosis, thalassemia, G6PD deficiency etc.
Abo abo was created in 1992.
If the first child was Rh positive it is less likely that the jaundice was due to Rh incompatibility unless you had an abortion earlier and did not take anti D. ABO incompatibility is more likely. If you took anti D after the first delivery because the first child was Rh positive then second child may not be affected.
There is no special procedure to follow for a group B recipient to get group O red cell transfusions. There are no A or B antigens present on the donor red cells, so no ABO incompatibility.
Your questions makes no sense. What is abo
Abo Dreth.