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All About Liver Cancer

Updated: 12/23/2023
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12y ago

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Liver cancer, also known as hepatocellular carcinoma (HCC), is a type of cancer that originates in the liver cells. The liver is a vital organ responsible for various functions, including filtering blood, detoxifying harmful substances, and producing essential proteins. Liver cancer can develop when normal liver cells undergo genetic mutations that cause uncontrolled growth.

Here are key aspects related to liver cancer:

Causes and Risk Factors:

Chronic Liver Diseases: Most cases of liver cancer are associated with underlying liver diseases, such as cirrhosis. Chronic hepatitis B or C infections, excessive alcohol consumption, and non-alcoholic fatty liver disease (NAFLD) can lead to cirrhosis, increasing the risk of liver cancer.

Viral Infections: Chronic infection with hepatitis B or C viruses is a major risk factor. These viruses can lead to persistent inflammation and liver damage.

Alcohol Consumption: Heavy and prolonged alcohol consumption can contribute to liver cirrhosis and increase the risk of liver cancer.

Non-Alcoholic Fatty Liver Disease (NAFLD): Obesity, Diabetes, and metabolic syndrome are linked to NAFLD, which, in some cases, may progress to liver cancer.

Symptoms:

Early stages may be asymptomatic.

As the cancer progresses, symptoms may include abdominal pain, unexplained weight loss, loss of appetite, jaundice (yellowing of the skin and eyes), and swelling in the abdomen.

Diagnosis:

Imaging Tests: CT scans, MRI scans, and ultrasound can detect tumors and assess their size and location.

Blood Tests: Elevated levels of certain liver enzymes may indicate liver damage.

Biopsy: A tissue sample is obtained from the liver for microscopic examination to confirm the presence of cancer cells.

Stages:

Liver cancer is staged based on the size of the tumor, extent of spread, and involvement of nearby structures. Staging helps determine the appropriate treatment approach.

Treatment Options:

Surgery: Surgical removal of the tumor or liver transplantation.

Ablation Therapy: Using heat or cold to destroy cancer cells.

Radiation Therapy: Targeted radiation to kill cancer cells.

Chemotherapy: Medications to kill cancer cells or inhibit their growth.

Targeted Therapy: Drugs targeting specific molecules involved in cancer growth.

Prevention:

Vaccination: Hepatitis B vaccination can prevent infection.

Screening: Regular screening for individuals at high risk, such as those with chronic liver diseases.

Prognosis:

The prognosis for liver cancer depends on factors like the stage at diagnosis, overall health, and response to treatment. Early detection and intervention improve outcomes.

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kalyani tallapaka

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9y ago

Liver cancer sometimes has no symptoms. Some people do experience fever along with sudden weight gain. The weight gain is contributed towards retaining fluids. A doctor can provide a person with all the information needed if there is a liver cancer prognosis.

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12y ago

The liver is the organ in the body that breaks down anything the body takes in and transforms them into chemicals that help the body run. It also takes any harmful things put into the body and removes it from the bloodstream. When people talk about liver cancer they can be referring to cancer that comes from the liver, known as primary liver cancer, or to cancer that started from another part of the body and has spread to the liver, this is known as secondary liver cancer.

Liver cancer is more often found in men than women and is the third most common cancer around the world. Other risk factors are age, weight, having a history of diabetes, and race. It has been found that older people, as well as overweight people develop liver cancer. Also, liver cancer is commonly found in Pacific Islanders and Asian-Americans. Primary liver cancer can be caused by any damage done to the liver, such as alcohol abuse, cirrhosis, chronic infections caused by hepatitis B and C, and birth defects. It can be spotted by a variety of symptoms such as weight loss, yellowing of skin and eyes, abdominal pain, enlarged liver, and chalky bowel movements.

If liver cancer is found, usually only a liver transplant or aggressive surgery can treat it with success. This works only if the tumor is very small and diagnosed at an early stage. There are medications that a patient takes orally to stop tumor growth. Patients can also undergo chemotherapy, but often this does not cure the cancer. Radiation therapy has also been shown to shrink tumors and kill cancer cells. The survival rate varies from person to person. About 50% of people diagnosed with liver cancer have a 5 year survival rate. There are many factors that can determine a person's survival rate. Often times, people with liver cancer have other conditions, like cirrhosis, that can lessen their success. Depending on whether the tumor is detected at an early stage and removed, and if a successful liver transplant is undergone, and there are no other serious problems with the liver, then the chances for survival are favorable.

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12y ago

Liver cancer is a form of cancer that begins in the cells of your liver. Liver cancer is one of the most common and deadly cancers in the world. Most individuals with liver cancer do not survive because symptoms typically do not develop until the cancer has progressed into a serious state. Understanding the symptoms of liver cancer can help you know when to see a doctor, and will give you the best chance for survival.

Risks of Developing Liver Cancer

Individuals with hepatitis B or a family history of liver cancer have an increased risk of developing liver cancer. Individuals suffering from cirrhosis of the liver due to alcohol consumption also are at risk of cancer forming in the liver. Individuals actively drinking are less likely to develop liver cancer. Most people who develop liver cancer after cirrhosis have stopped drinking. The reason is because the liver tries to heal itself by reproducing cells. The cells are often mutated because of liver damage and cancer forms.

Symptoms

Symptoms are not usually present at the initial stage of liver cancer. Some individuals experience vague symptoms such as fatigue, night sweats, chills, and fever. As the cancer becomes more advanced, symptoms that may appear include jaundice, pain or swelling in the upper portion of the abdomen on the right side of the body, and itching all over the body. Advanced symptoms may also include loss of appetite, nausea, vomiting, and general weakness in the body.

Diagnosis and Treatment

A doctor may order an ultrasound or CT scan for a patient experiencing symptoms related to liver cancer. A CT scan and an MRI can show a tumor as small as one centimeter and can help determine the stage of the cancer. A biopsy must be performed to determine if a tumor is benign or malignant. Liver cancer is difficult to treat because it is usually found at a late stage. Patients with liver cancer in the early stage have the best chance of successfully having the tumor removed through surgery. In some cases, chemotherapy can cause a tumor to shrink to a point where it can be successfully removed through surgery.

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12y ago

Liver cancer is considered one of the most widespread types of cancer in the world. There are other types of cancer that take form in and affect the liver; however, not all of these are considered to be liver cancer. For instance, cancer that starts in another part of the body then spreads to the liver is not liver cancer. Liver cancer is specifically characterized by a cancer that takes form right in the cells of the liver itself.

Symptoms

Often times a person will shown no symptoms in the early stages of liver cancer. Typical symptoms of liver cancer include loss of appetite, unexplained weight loss, pain in the upper abdomen, vomiting and nausea, fatigue and weakness, swelling of the abdomen, chalky and white stools, and a yellow tint to the skin and whites of the eyes. It is important to see you doctor if you begin to notice any of the symptoms of liver cancer, as early detection is vital in a successful recovery.

Causes and Risk Factors

Healthcare professionals are still unclear as to what exactly causes some cases of liver cancer; however, in certain cases the cause is well-known. For example, some cases of liver cancer can be caused by a chronic hepatitis infection. Other risk factors for developing liver cancer include being a male, having cirrhosis of the liver, having a history of certain hereditary liver diseases, a history of diabetes, suffering from nonalcoholic fatty liver disease, excessive alcohol use and obesity.

Treatment

The type of treatment a liver cancer patient will receive depends much on the stage of the disease, as well as the age and general health of the patient. Treatment options for liver cancer include surgery to remove part of the liver, transplant surgery, cryoablation (freezing of the cancer cells), radiofrequency ablation (heating of the cancer cells), alcohol injection into the tumor, chemotherapy, radiation or targeted drug therapy. Sometimes, these treatments may be used in conjunction with one another for the best possible outcome.

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