Yaws

Answer 1

Definition

Yaws is a long-term (chronic) infection that mainly affects the skin, bones, and joints.

Alternative Names

Frambesia tropica

Causes, incidence, and risk factors

Yaws is an infection caused by the spiral-shaped bacteria, Treponema pallidum, subspecies pertenue. It is closely related to the bacteria that cause syphilis, but this disease is not sexually transmitted. Yaws mainly affects children in rural, warm, tropical areas, such as the Caribbean Islands, Latin America, West Africa, India, and Southeast Asia.

Yaws is transmitted by direct contact with the skin sores of infected people.

Symptoms

About 2 - 4 weeks after infection, the person develops a sore called a "mother yaw" where bacteria entered the skin. The sore is a growth that looks like a raspberry. It is usually painless. These sores may last for months. More sores may appear shortly before or after the mother yaw heals.

Other symptoms include:

• Bone pain
• Scarring of the skin
• Swelling of the bones and fingers

In the final stage, sores on the skin and bones can lead to severe disfigurement and disability. This occurs in up to 1 in 5 people who do not get antibiotic treatment.

Signs and tests

A sample from a skin sore is examined under a special type of microscope (darkfield examination). There is no blood test for yaws. However, the blood tests for syphilis may be positive in yaws because the two conditions are closely related.

Treatment

Treatment involves a single dose of a specific type of penicillin, or or 3 weekly doses for later stage disease. It is rare for the disease to return.

Expectations (prognosis)

If treated in its early stages, yaws can be cured. Skin lesions may take several months to heal.

By its late stage, yaws may have already caused damage to the skin and bones. It may not be fully reversible, even with treatment.

Complications

Yaws may damage the skin and bones, affecting the appearance and ability to move. It can also cause deformities of the legs, nose, palate, and upper jaw.

Calling your health care provider

Contact your health care provider if you or your child has sores on the skin or bone that don't go away, and you have stayed in tropical areas where yaws is known to occur.

Prevention

Widespread campaigns in the 1950s and 1960s to wipe out yaws through penicillin treatment have dramatically decreased the number of cases worldwide.

References

Hook III EW. Nonsyphilitic Treponematoses. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 341.

Answer 2

Definition

Yaws is a long-term (chronic) infection that mainly affects the skin, bones, and joints.

Alternative Names

Frambesia tropica

Causes, incidence, and risk factors

Yaws is an infection caused by the spiral-shaped bacteria, Treponema pallidum, subspecies pertenue. It is closely related to the bacteria that cause syphilis, but this disease is not sexually transmitted. Yaws mainly affects children in rural, warm, tropical areas, such as the Caribbean Islands, Latin America, West Africa, India, and Southeast Asia.

Yaws is transmitted by direct contact with the skin sores of infected people.

Symptoms

About 2 - 4 weeks after infection, the person develops a sore called a "mother yaw" where bacteria entered the skin. The sore is a growth that looks like a raspberry. It is usually painless. These sores may last for months. More sores may appear shortly before or after the mother yaw heals.

Other symptoms include:

• Bone pain
• Scarring of the skin
• Swelling of the bones and fingers

In the final stage, sores on the skin and bones can lead to severe disfigurement and disability. This occurs in up to 1 in 5 people who do not get antibiotic treatment.

Signs and tests

A sample from a skin sore is examined under a special type of microscope (darkfield examination). There is no blood test for yaws. However, the blood tests for syphilis may be positive in yaws because the two conditions are closely related.

Treatment

Treatment involves a single dose of a specific type of penicillin, or or 3 weekly doses for later stage disease. It is rare for the disease to return.

Expectations (prognosis)

If treated in its early stages, yaws can be cured. Skin lesions may take several months to heal.

By its late stage, yaws may have already caused damage to the skin and bones. It may not be fully reversible, even with treatment.

Complications

Yaws may damage the skin and bones, affecting the appearance and ability to move. It can also cause deformities of the legs, nose, palate, and upper jaw.

Calling your health care provider

Contact your health care provider if you or your child has sores on the skin or bone that don't go away, and you have stayed in tropical areas where yaws is known to occur.

Prevention

Widespread campaigns in the 1950s and 1960s to wipe out yaws through penicillin treatment have dramatically decreased the number of cases worldwide.

References

Hook III EW. Nonsyphilitic treponematoses. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 341.

Reviewed By

Review Date: 02/23/2010

David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.