In the owners manual it tells. On my 93 lesabre I had to jump two of the connetors on the code reader
how do i program keyless remote for 2000 Buick LeSabre
You can do it but be careful not to break the prongs
Because its a 1988 Buick LeSabre
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To program the remote control key for a 2004 Buick LeSabre, first, insert the key into the ignition and turn it to the "On" position without starting the engine. Within five seconds, press and hold the "Unlock" button on the remote for about 15 seconds, then press the "Lock" button while continuing to hold the "Unlock" button. Release both buttons, and the locks should cycle to indicate successful programming. Repeat this process for any additional remotes.
I found some great deals on keyless remotes on ebay. You can also order them from an auto parts store or you Buick dealer.