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A response is always triggered by a stimulus. One example is in a neuron (nerve cell). Once a sensory stimulus is witnessed (a stimulus from one of the 5 senses), the cell hits an action potential, and the response is carried out.

Simply put: A human eye is closed. Once the eye opens thousands of sensors in the eye pick up the photons bouncing off all objects (stimulus), and the human is able to see (response).

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