Beta-oxidation is the major pathway by which fatty acids are metabolized. However, there are other minor pathways for fatty acid metabolized. These include alpha-oxidation (for branched fatty acids) and omega-oxidation.
energy in the form of Adenosine Triphosphate (ATP). This process occurs in the mitochondria, where glucose is broken down through glycolysis and the citric acid cycle, amino acids are converted into intermediates that enter these pathways, and fatty acids undergo beta-oxidation to produce ATP. The liberated energy from these processes fuels cellular functions and activities.
Fats are composed of fatty acids, which are chains of carbon and hydrogen atoms. They also contain glycerol, a type of alcohol that connects the fatty acids together to form triglycerides. Different types of fats can vary in the length and saturation of their fatty acid chains.
The connecting link between the hexose monophosphate shunt (pentose phosphate pathway) and lipid synthesis is the generation of NADPH. NADPH produced during the pentose phosphate pathway is utilized as a reducing equivalent in the fatty acid synthesis pathway. This NADPH provides the necessary reducing power for the synthesis of fatty acids from acetyl-CoA.
Glycerol
Fatty acids produce more ATP compared to glucose due to their higher energy density. When metabolized in the mitochondria through beta-oxidation, fatty acids yield more acetyl-CoA molecules per carbon atom, leading to increased ATP production through the citric acid cycle and oxidative phosphorylation. This higher ATP yield makes fatty acids a more efficient energy source for the body, especially during prolonged periods of low-intensity exercise or fasting.
glycolysis
The site where fibers can be metabolized to short-chain fatty acids is in the colon. Fiber that remains undigested in the small intestine travels to the colon where it is fermented by gut bacteria, resulting in the production of short-chain fatty acids. These fatty acids play a key role in maintaining gut health and have various benefits for the body.
Coconut oil is a common source of medium-chain fatty acids. These fatty acids are metabolized differently than long-chain fatty acids, making them a popular choice for energy production in the body.
The common pathway for oxidation of products of glucose and fatty acids catabolism is the citric acid cycle (also known as the Krebs cycle). In this cycle, acetyl-CoA derived from both glucose (from glycolysis) and fatty acids (from beta-oxidation) is oxidized to produce NADH and FADH2, which are then used to generate ATP through oxidative phosphorylation in the electron transport chain.
I believe brown fat (commonly found in neonates) is metabolized by lipase into free fatty acids which are then hydrolyzed into glycerol and non estrified fatty acids.
When fats are metabolized, the fatty acids enter the reactions of the citric acid cycle (Krebs cycle) where they are broken down further to produce energy in the form of ATP. This cycle takes place within the mitochondria of the cells.
Fats must be converted to fatty acids and glycerol before they can be metabolized in aerobic cellular respiration. This breakdown process occurs in the cytoplasm of the cell through a series of enzymatic reactions. Once converted, fatty acids can enter the mitochondria to undergo beta-oxidation and produce acetyl-CoA for the citric acid cycle.
The building blocks in the body's synthesis and elongation of fatty acids are acetyl-CoA and malonyl-CoA. These molecules are used as substrates in the fatty acid synthesis pathway, where they undergo a series of enzymatic reactions to form long-chain fatty acids.
The glyoxylate pathway occurs in the peroxisomes of eukaryotic cells and in the cytoplasm of prokaryotic cells. It is a metabolic pathway that allows some organisms to convert fatty acids into carbohydrates for energy production.
Cells do not ferment fatty acids because fatty acids cannot be broken down through glycolysis, which is the main metabolic pathway for fermentation. Instead, fatty acids are broken down through beta-oxidation in the mitochondria to produce acetyl-CoA, which then enters the citric acid cycle for energy production.
Fatty acids are converted into acetyl-CoA through beta-oxidation in the liver before being further metabolized to produce energy. Since they are broken down and utilized for energy production, fatty acids are not typically excreted in urine. Instead, any excess fatty acids are stored as triglycerides in adipose tissue for later use.
Apart from glucose you have Fatty acids, Glycerol and Proteins, which enters the Creb's cycle to yeald ATP, after break down.