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There are many possibilities. If the mutations occurs but it does not change the amino acid sequence due to the redundancy (codon degeneracy) of the genetic code, then the mutation is silent and no effect is observed. If the mutation occurs and the amino acid sequence is changed, but the new amino acid has similar properties to the original amino acid (e.g. aspartic acid -> glutamic acid) and the position of the mutation is far away from the active site, then the mutation will likely have minimal effects on the structure and function of the protein. However, if the mutation changes the amino acid sequence such that the new amino acid has a very different property to the original (lysine -> valine) or if the mutation occured close to the acitive site, then it is very likely that the structure and function of the protein will be compromised. Lastly, there is also the marginal chance that the last type of mutation described above actually increases the effectiveness of the protein. Though this is exceedingly rare, it is the driving force behind evolution.

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14y ago
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Wiki User

9y ago

If a gene that codes for a particular enzyme is altered by a mutation, the enzyme will not function properly. The mutated gene will not be recognized by the receptor site of the enzyme, and its proper function will not activated.

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14y ago

It would depend on the enzyme (there are many) and the type of mutation (substitution, deletion, etc). Some mutations can cause fairly minor disturbances in the protein and on the organism as a whole, while others cause the enzyme to be non-functional. Some non-functional proteins will shorten life-expectancy, and others will cause the zygote to be nonviable.

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Marian Ortiz

Lvl 2
3y ago

The substrate cannot fit the enzyme

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Q: If a gene was changed by mutation then what do you think would happen to the shape of enzyme built by the gene?
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How does an insertion sequence cause a mutation?

In the DNA, the sequence of nucleotides determines how proteins are built, with each segment of three nucleotides encoding a single amino acid. When one nucleotide is inserted into the sequence, the whole sequence shifts, and all the triples are changed completely, which can cause detrimental mutations.


How does glucose react with glucose oxidase?

Since you know what Glucose Oxidase is I'm assuming you know what enzymes are. If not, an enzyme is a protein that catalyzes chemical reactions. Glucose oxidase is the enzyme built specifically for Glucose. Glucose Oxidase binds to the six-carbon sugar Glucose and aids the organism in breaking it down into metabolites.


Why do denatured enzymes become disfunctional?

An enzyme's ability to function comes from its shape, which is a result of the folding of the amino acid chain that it's made of. Enzymes act on their substrates (just a fancy word for whatever molecule or chemical or anything that an enzyme acts on) on a certain part of the enzyme called the active site. This can be modeled by an example such as a lock and a key. The lock would be the enzyme, and the key the substrate. It's a very specific fit. When an enzyme becomes denatured, it starts to unfold, which changes its shape. Changing the shape of the active site, means that the substrate no longer fits, just as the key would no longer fit if you heated the lock until it melted. Since the substrate can no longer bind to the enzyme's active site, the enzyme is no longer effective.


What happens if there's a mutation in your body cells?

The sequence of the nitrogenous bases changes (and sometimes some bases are added to the sequence or completely removed).


How can a mutation in a DNA base sequence cause a change in a proteins?

dna in a cell needs protein and chromosomes.

Related questions

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Change in the nucleotide sequence of DNA causing proteins to be built differently?

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In the DNA, the sequence of nucleotides determines how proteins are built, with each segment of three nucleotides encoding a single amino acid. When one nucleotide is inserted into the sequence, the whole sequence shifts, and all the triples are changed completely, which can cause detrimental mutations.


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