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The SSRI class is neither antagonist nor agonist. They are re-uptake inhibitors.

To the extent of my knowledge (I am NOT a doctor), a serotonin:

agonist enhances production of sertonin at the source neuron,

antagonists blocks binding of serotonin to the target neuron effectively blinding it,

re-uptake inhibitors block the destruction of serotonin, effectively letting it act for longer.

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Q: Is the drug ssri an antagonist or agonist?
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