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Sometimes mutations in DNA can cause control of the cell cycle to fail. What might happen if such a mutation occurred in a person's DNA?
Wiki User
∙ 6y ago
The failure of DNA replication during the cell cycle can cause mutations. If such mutations occurred in a person's DNA, the person can end up getting cancer.
Laury Roob
Nannie Keeling
The failure of DNA replication during the cell cycle can cause mutations. If such mutations occurred in a person's DNA, the person can end up getting cancer.
Wiki User
∙ 9y agoThe failure of DNA replication during the cell cycle can cause mutations. If such mutations occurred in a person's DNA, the person can end up getting cancer.
Wiki User
∙ 9y agothey might get cancer
Wiki User
∙ 6y agoThe person might get cancer
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Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
What are the affects of a mutation?
MutationA mutation produces an abnormal gene, which may limit, not effect, or enhance the ability of an organism to survive and reproduce. A mutation does not have any set effects on the organism, as the mutated gene may not change the appearance of the organism. Mutations of normal cells in an organism can cause cancer, as cancer is just normal cells that have been damaged in such a way as to grow out of control.
What type of mutations do not effect phenotype?
Synonymous mutations. These are mutations that happen in the coding regions of genes that change one nucleotide for another. However, because of redundancy in the genetic code (where one amino acid may be coded for by more than one nucleotide sequence) the amino acid sequence of the protein isn't altered. Mutations that occur in non-coding, non-control regions of the genome also don't affect phenotype. You may also wish to look at Wikipedia's entry on silent mutations.
How do mutations in DNA structure cause changes in protein function?
In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transpositions and mutagen chemicals, as well as errors that occur during meiosis or DNA replication.[1][2][3] They can also be induced by the organism itself, by cellular processes such as hyper mutation.Mutation can result in several different types of change in sequences;(DNA) these can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Studies in the fly Philosophic melanoma suggest that if a mutation changes a protein produced by a gene, this will probably be harmful, with about 70 percent of these mutations having damaging effects, and the remainder being either neutral or weakly beneficial.[4] Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to remove mutations.[1]Therefore, the optimal mutation rate for a species is a trade-off between costs of a high mutation rate, such as deleterious mutations, and the metabolic costs of maintaining systems to reduce the mutation rate, such as DNA repair enzymes.[5] Viruses that use RNA as their genetic material have rapid mutation rates,[6] which can be an advantage since these viruses will evolve constantly and rapidly, and thus evade the defensive responses of e.g. the human immune system.[7]
How are mutation and cancer related?
Mutations are changes in the DNA sequence of a cell's genes. These changes can occur for various reasons, including exposure to environmental factors, aging, errors during DNA replication, or inherited genetic mutations. When mutations affect genes that regulate cell growth, division, and repair, they can contribute to the development of cancer. Here's how mutations are related to cancer: Uncontrolled Cell Growth: Mutations in certain genes, known as oncogenes, can lead to the activation of proteins that promote cell growth. When these genes are mutated, they may signal cells to continuously divide and grow, contributing to the formation of tumours. Loss of Growth Regulation: Mutations in tumor suppressor genes can result in the loss of normal regulatory functions. Tumor suppressor genes normally inhibit cell division or promote programmed cell death (apoptosis) when necessary. Mutations in these genes can lead to uncontrolled cell growth. DNA Repair Deficiencies: DNA repair genes are responsible for fixing errors or damage in the DNA sequence. Mutations in these genes can result in an accumulation of genetic mistakes, increasing the likelihood of additional mutations and promoting cancer development. Genomic Instability: Mutations can contribute to genomic instability, where the DNA within cells becomes more prone to further mutations. This can create a cascade effect, leading to the accumulation of genetic changes that drive cancer progression. Inherited Mutations: Some individuals inherit specific mutations that predispose them to a higher risk of developing certain types of cancer. While these inherited mutations may not directly cause cancer, they increase susceptibility to the disease. Understanding the genetic basis of cancer has led to advancements in targeted therapies and precision medicine. Identifying specific mutations in cancer cells allows for the development of treatments that target the underlying genetic abnormalities, offering more effective and tailored approaches to cancer therapy. Research in genomics continues to play a crucial role in unraveling the complex relationship between mutations and cancer.
What seems to determine the magnitude of a mutation's effect?
Control genes determine the magnitude of a mutation's effect. Mutations in these parts of the genome can substantially change the way the organism is built.
A change in the genetic material of a cell is called?
Cancer- certain mutations (changes) in a cell's genetic material may cause that cell to reproduce with out control.
Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
How does mutation in the body cells cause damage?
Some mutaions of DNA in body cells affect genes that control cell division. This can result in the cells growing and dividing rapidly, producing cancer. If this is not right I'm sorry. I'm a little rusty on biology.
How does cancer begin at the cellular level and how does a healthy immune system work to prevent it?
In cellular level Cancer starts with a molecular mutation that effects the DNA of the cell. When this mutation occurs there are some control mechanisms to repair the effected part of the DNA but sometimes the control mechanisms may not work properly and the control on the dmged cell vanish and the cell starts to proliferate repeatedly. usually normal mutations in the DNA are fixed and if it is not fixable the cell goes down a process called apoptosis and that refers the cell is suiciding but some mutations may occur on some genes which are responsible of the activity of tumor supressing and when this kind of genes are effected the seed of cancer is become sown.
What are the affects of a mutation?
MutationA mutation produces an abnormal gene, which may limit, not effect, or enhance the ability of an organism to survive and reproduce. A mutation does not have any set effects on the organism, as the mutated gene may not change the appearance of the organism. Mutations of normal cells in an organism can cause cancer, as cancer is just normal cells that have been damaged in such a way as to grow out of control.
Why is a carcinogenic mutation not inheritable?
Not all mutations that occur are inheritable. Inheritable means that the mutations are able to be passed on from an organism to the organism's offspring. Only mutations that occur on the gametes (sex cells) are inheritable. For example, if a mutation occurs in a somatic cell (body cell), the mutation will never be inherited by the organism's offspring because that mutation is not part of the cells that pass on genetic information to offspring. Somatic cells only create new cells for the individual's body, whereas gametes have the ability to be passed on to offspring.
What are cancer mutations?
Some mutations cause cells to lose control over cell division
Why not all mutation cause cancer?
Many mutations are actually benign. They may occur in areas of DNA which don't code for anything, or a mutation may occur in a gene that isn't expressed (ie, isn't "turned on" and being used to make proteins) in that particular cell. Even when a mutation occurs in an expressed gene, it may still be benign since different codons can translate into the same amino acid. For instance, the DNA sequences 'GGA' and 'GGC' both code for the amino acid proline. This means that a mutation from 'GGA' to 'GGC' would still cause the same amino acid to be synthesized, and no bad effect would result. Even when a mutation is harmful, the result isn't always cancer. Many other diseases, such as hemophilia and Huntington's disease, are genetic and would have first come about as mutations. Cancer occurs when mutations happen in genes that control cell growth, division, and death.
Which mutation can disrupt the control of cell reproduction?
Cancer
How do we get cancerous cells?
The current theory of cancer is "one mutation, one cancer". According to this theory, a dividing cell in your body acquires a genetic mutation that somehow disrupts the normal control mechanisms. This mutated cell then continues to grow and divide. If the immune system doesn't destroy the mutated cell, and the cell is able to maintain nutrient flow into itself, it will eventually show up as a cancerous mass. However, new research is unveiling just how complicated the development of cancer is. For instance, as the mutated cells keep dividing, they keep acquiring new mutations which can significantly change the behavior of the overall tumor. Also, sometimes just one mutation is not sufficient to cause a cell to become cancerous - in some cancers it appears there have to be a series of specific mutations before the cells start to exhibit cancerous properties.
What type of disease can occur from mutations that can disrupt the control of cell reproduction?
cancer
