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Artificial enzymes do now exist. David Baker and his research team at the Baker Laboratory created an enzyme that catalyses a Kemp elimination - that is a reaction for proton transfer from carbon. The names of the best two that they came up with is

KE59 and KE70. This was done in 2007, so I assume there are more by now.

The reference for the entire article is"

Rothlisberger et al. 2007, 'Kemp elimination catalysts by computational enzyme design', Nature, 453, pp. 190.

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