Of course, there can be many outcomes from no problems to sickle cell disease to fetal death. Some mutations really cause no problems, some can cause a disease and some are so damaging it can cause the death of the unborn child.
There are no differences in the amino acids in human hemoglobin and wolf hemoglobin.
Genetic mutations over time likely caused changes in the amino acid sequence from gorillas to humans. These mutations could have arisen from environmental factors, natural selection, or genetic drift. As a result, differences in amino acids between gorillas and humans have accumulated over millions of years of evolution.
A change in the nucleic acids that carry information to make hemoglobin, such as a mutation, could result in a different amino acid being incorporated into the hemoglobin protein sequence. This can lead to structural changes in hemoglobin, affecting its ability to bind oxygen, potentially causing disorders like sickle cell anemia.
A mutation that causes the code for the wrong amino acid (apexvs.com)
A mutation can change a codon for one amino acid into a different codon for the same amino acid through a process called silent mutation. This type of mutation occurs when a change in the DNA sequence does not alter the amino acid that is coded for, resulting in the same protein being produced.
no
sickle cell disease
Hemoglobin is a protein, which is composed of linked amino acids.
loss of only one amino acid from the normal hemoglobin molecule
Sickle cell
17 amino acid differences
A single amino acid substitution, such as the one in sickle cell anemia where glutamic acid is replaced by valine, can cause hemoglobin molecules to stick together due to a change in the structure of the protein. This structural change leads to the formation of abnormal hemoglobin polymers that can distort the shape of red blood cells, leading to their sickling and contributing to various complications.
Sickle-cell anemia
Glutamate is substituted for a valine at position 6. But this is not an amino acid problem, it's the construction of hemoglobin that's in error.
There are no differences in the amino acids in human hemoglobin and wolf hemoglobin.
Genetic mutations over time likely caused changes in the amino acid sequence from gorillas to humans. These mutations could have arisen from environmental factors, natural selection, or genetic drift. As a result, differences in amino acids between gorillas and humans have accumulated over millions of years of evolution.
Yes, it already has by changing the amino acid you have a mutation. That one amino acid counld be in the active site of an enzyme and that one amino acid being changed could result in loss of function or reduction in function of the enzyme. Sickle cell animea is caused by a single such amino acid substiution.