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Of course, there can be many outcomes from no problems to sickle cell disease to fetal death. Some mutations really cause no problems, some can cause a disease and some are so damaging it can cause the death of the unborn child.
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What could have been responsible for the change in amino acid from gorillas to humans?
The proteins in the amino-acids might have been responsible for the change in the hemoglobin between gorillas and humans.
Do transcription and translation change from amino acid to nucleic acid?
no
What is a genetic mutation that does not result in a change in the amino acid sequence of the resulting protein?
It is neutral mutation. Codons are made up of 3 base pairs. This gives 64 different combinations, but there are only 20 amino acids, so some different codons will code for the same amino acid. When the base pair that is changed doesn't cause a change in the amino acid it codes for, then ultimately nothing happens
How would the amino acid sequence produced by the mutant strand compare to the amino acid sequence produced by series 1?
one amino acid in the sequence would change
What is a non synonymous polymorphism?
Substitutions that result in amino acid replacements are said to be nonsynonymous while substitutions that do not cause an amino acid replacement (such as a GGG to GGC change - both codons still encode glycine) are said to be synonymous substitutions
Is hemoglobin an amino acid?
no
What diseases arises from an amino acid change in protein hemoglobin?
sickle cell disease
What is the relation of amino acid to sickle cell hemoglobin?
Hemoglobin is a protein, which is composed of linked amino acids.
What is the difference between normal and sickle cell hemoglobin?
loss of only one amino acid from the normal hemoglobin molecule
What could have been responsible for the change in amino acid from gorillas to humans?
The proteins in the amino-acids might have been responsible for the change in the hemoglobin between gorillas and humans.
What common genetic variation which causes a change in the amino acid sequence in the structure of hemoglobin leads to what disease?
Sickle cell
What is differ ence between the amino acid sequences of the hemoglobin in humans and the hemoglobin in frogs?
There are 9 differences
How does human hemoglobin compare with horse's?
17 amino acid differences
What type of mutation in the DNA leads to a single change in the amino acid sequence of the protein?
Yes, it already has by changing the amino acid you have a mutation. That one amino acid counld be in the active site of an enzyme and that one amino acid being changed could result in loss of function or reduction in function of the enzyme. Sickle cell animea is caused by a single such amino acid substiution.
In which hereditary disease does abnormal hemoglobin differ from normal hemoglobin by only a single amino acid?
Sickle-cell anemia
In sickle cell what amino acid is changed?
Glutamate is substituted for a valine at position 6. But this is not an amino acid problem, it's the construction of hemoglobin that's in error.
How does sickle cell hemoglobin differ from normal hemoglobin?
Sickle cell hemoglobin differs from normal hemoglobin primarily due to a single amino acid substitution in the hemoglobin protein chain. In sickle cell disease, a person inherits two copies of an abnormal hemoglobin gene, usually referred to as HbS. In normal hemoglobin (HbA), the amino acid glutamic acid is present at a specific position in the beta chain of the hemoglobin protein. However, in sickle cell hemoglobin (HbS), this glutamic acid is replaced by valine due to a genetic mutation. This change causes the hemoglobin molecules to stick together under certain conditions, forming long, rigid structures that distort red blood cells into a sickle or crescent shape.
