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As the bilayer contains hydrophobic fatty acid tails, water-soluble molecules cannot diffuse directly through. However, lipid soluble molecules such as oxygen can diffuse directly through. Overall, for a molecule to be able to diffuse directly through it must be lipid-soluble, relatively small and non-polar.

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Q: What particles can diffuse directly through the lipid bi-layer?
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Is glucose permeable through phospholipid bilayer?

Glucose does not readily diffuse across a lipid bilayer. In order for glucose to travel into the cell, it needs the help of a transport protein. This is called a facilitated diffusion.


Which substances readily diffuse through the membrane?

Small and non-polar molecules can readily pass through the cell membrane. They follow the concentration gradient, moving from the higher concentration area to the region of lower concentration.


What substance will diffuse through a membrane?

The three substances that can diffuse through a cell membrane are CO2, O2, AND H2O.


Is the lipid bilayer permeable to most water-soluble substances?

The lipid bilayer is impermeable to most water-soluble substances.The bilayer, most of which is a phospholipid bilayer, is permeable only to small, non-polar substances.In nature, the most common compounds to pass through the bilayer are carbon dioxide and oxygen.Scientists differ over how much water passes in and out of cells through the bilayer; some passes through special transport proteins called aquaporins.


Is the lipid bilayer permeable to most water soluble substances?

The lipid bilayer is impermeable to most water-soluble substances.The bilayer, most of which is a phospholipid bilayer, is permeable only to small, non-polar substances.In nature, the most common compounds to pass through the bilayer are carbon dioxide and oxygen.Scientists differ over how much water passes in and out of cells through the bilayer; some passes through special transport proteins called aquaporins.

Related questions

Why water molecules cannot diffuse directly through the phosolipids bilayer?

Hydrophobic centre of the phospholipid bilayer prevents non-liquid soluble molecules from passing through.


What does this phrase mean globular proteins that span the lipid bilayer?

I believe the 'lipid-bilayer' refers to the membrane of a cell. A globular protein is something that takes on a roughly spherical shape. In cells proteins span the outside of a cell to the inside to help with the diffusion of molecules or especially ions that do not diffuse directly through the membrane.


Is glucose permeable through phospholipid bilayer?

Glucose does not readily diffuse across a lipid bilayer. In order for glucose to travel into the cell, it needs the help of a transport protein. This is called a facilitated diffusion.


What particles could diffuse easily through a cell membrane sodium and oxygen?

Oxygen (O2)


What is the purpose of the proteins in the bilayer?

They can be used to carry things across the membrane. for example, glucose is too large to diffuse through, so a protein must be used to carry it.


Which substances readily diffuse through the membrane?

Small and non-polar molecules can readily pass through the cell membrane. They follow the concentration gradient, moving from the higher concentration area to the region of lower concentration.


What types of molecules diffuse through the cell membranes by facilitated diffusion?

molecules that can survive the hydrophobic interior of the lipid bilayer


Transport protein that provides a tubelike opening in the plasma membrane through which particles can diffuse?

Channel Protein.


Are non polar molecules able to cross lipid bilayer?

Yes, Since the lipid bilayer of cells is nonpolar, only non-polar substances can pass directly through the bilayer without the need for any help by membrane transport proteins.


Why don't ions pass through cell membran?

Only small and uncharged particles can pass through the nonpolar part of the membrane interior. Ions are charged and won't pass through a membrane by passive diffusion. Certain ions do pass through membranes by other mechanisms, though.


Explain why osmosis is different from diffusion?

Osmosis is specifically the movement of water from an area of high water concentration to an area of low water concentration across a small semipermeable membrane. Diffusion is the movement of other particles from an area of high concentration to an area of low concentration, either directly across the phospholipid bilayer or through protein channels imbedded in the phospholipid bilayer


How does salts enter the cell?

Salts are soluble. The phospholipid bilayer membrane of cell walls are permeable to water and thus allow water and water-soluble substances, like salts, diffuse through.