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Say the part of the gene that is mutated does not change the amino acid sequence of the protein made through the mRNA; hydrophobic amino acid stays hydrophobic. We have many of these small nucleotide polymorphisms in our genomes and they are useful trackers of human migrations, for instance.
What else can I help you with?
Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
What effect does insertion have on the protein produced?
Insertion of additional amino acids into a protein can alter its structure and function. The inserted amino acids may disrupt the protein's folding or change its active site, affecting its ability to interact with other molecules or carry out its specific biological function. Overall, insertion can lead to changes in the protein's properties and potentially impact its overall biological function.
Why can some gene mutatuions be harmful while others have no effect?
Let's consider a simple example: protein-coding genes. Mutations, or changes in the DNA sequence of the gene, can alter the amino acid sequence of the protein it codes for, if the new sequence translates into different amino acids. Because the genetic code is degenerate, some amino acids are specified by multiple codons, so some mutations may not alter the amino acid sequence at all. Such mutations, called synonymousmutations, have no affect on the protein. Mutations that alter the amino-acid sequence of the protein, called non-synonymousmutations, may or may not have an affect. Most proteins can tolerate some changes to that sequence and not be significantly affected, but if the sequence change is large enough, or occurs at a critical point so that the structure of the protein is significantly altered, then the protein may become non-functional. If that protein is essential to an organism, such a mutation may be lethal.
Why do some kinds of point mutations cause greater changes in proteins than others?
Because not every point mutation changes the protein. If it doesn't change, we call it a silent mutation or when one letter is deleted at the beginning, than the whole chain changes, but if it's at the end only the and changes so it's a bigger effect on the protein :p
Why is is it possible for a point mutation to have no affect on the protein produced?
A point mutation can have no effect on the protein produced if it occurs in a non-coding region of the gene, such as an intron. In coding regions (exons), silent mutations can also occur where the mutation leads to a codon that still codes for the same amino acid, preserving the protein's function. Additionally, some amino acid substitutions might not impact the protein's structure or function due to redundancy in the genetic code or similarities in amino acid properties.
Do all mutations affect the protein results?
No. Point mutations may have no effect on the protein, however, they can also be very harmful.
Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
How do mutations impact patters of inheritance?
they can be neutral and have no effect, improve a protein and be beneficial, result in a protein that does not work, which may cause disease
What effect does insertion have on the protein produced?
Insertion of additional amino acids into a protein can alter its structure and function. The inserted amino acids may disrupt the protein's folding or change its active site, affecting its ability to interact with other molecules or carry out its specific biological function. Overall, insertion can lead to changes in the protein's properties and potentially impact its overall biological function.
How is it possible for a point mutation to have no effect on the function of gene?
If the point mutation does not change the protein to be translated in the 3-letter sequence, then it will have no effect on the gene's function.
Why can some gene mutatuions be harmful while others have no effect?
Let's consider a simple example: protein-coding genes. Mutations, or changes in the DNA sequence of the gene, can alter the amino acid sequence of the protein it codes for, if the new sequence translates into different amino acids. Because the genetic code is degenerate, some amino acids are specified by multiple codons, so some mutations may not alter the amino acid sequence at all. Such mutations, called synonymousmutations, have no affect on the protein. Mutations that alter the amino-acid sequence of the protein, called non-synonymousmutations, may or may not have an affect. Most proteins can tolerate some changes to that sequence and not be significantly affected, but if the sequence change is large enough, or occurs at a critical point so that the structure of the protein is significantly altered, then the protein may become non-functional. If that protein is essential to an organism, such a mutation may be lethal.
Why do some kinds of point mutations cause greater changes in proteins than others?
Because not every point mutation changes the protein. If it doesn't change, we call it a silent mutation or when one letter is deleted at the beginning, than the whole chain changes, but if it's at the end only the and changes so it's a bigger effect on the protein :p
Why is is it possible for a point mutation to have no affect on the protein produced?
A point mutation can have no effect on the protein produced if it occurs in a non-coding region of the gene, such as an intron. In coding regions (exons), silent mutations can also occur where the mutation leads to a codon that still codes for the same amino acid, preserving the protein's function. Additionally, some amino acid substitutions might not impact the protein's structure or function due to redundancy in the genetic code or similarities in amino acid properties.
Are all DNA mutations detrimental?
Nope! Sometimes mutations are "silent mutations", this means that changing out the base does not change the amino acid made (as many amino acids are coded by about 3 different base combinations) Also, the mutation may only swap out an amino acid with a similar one, causing no change in the function of the protein it codes for. A lot of times, several AA's can be altered (even w/ very different AA's), and the protein structure/function can remain the same. Also.... DNA mutations that result in phenotypic mutations are sometimes a good thing: hence evolution... many small mutations causing an advantage over time. :) So mostly mutations that cause a base to swap out for another one are safe. Those that delete or insert a base change the reading frame and that's bad!
How are mutations expressed?
Mutations are expressed through changes in DNA sequence, leading to altered protein production, which can result in various phenotypic changes. These changes can be beneficial, harmful, or neutral depending on the specific mutation and its effect on the organism. Mutations are ultimately reflected in an organism's traits and characteristics.
What are the impact of mutations and how mutations can have no impact?
Mutations are usually anomalies in the sequence of a particular strand of DNA. The change is the sequence can be of various kinds and their individual effects vary. Sometimes mutations occur but they are never expressed. In such cases, on the whole, the mutation has had no impact. Changes in a single nucleotide can change the reading frame for protein coding regions and can cause misreading of the genetic code. For example, nonsense mutations caused by the exchange of a nucleotide leading to a stop codon can cause truncation of a protein. On the other hand, we can have silent mutations which show no effect because the nucleotide that has been exchanged does not cause change in amino acid sequence. So this would be an example of a mutation which shows no effect.
Why do some mutations have no effect?
Some mutations have no or little effect due to the redundancy of the DNA code.DNA consists of pairs of codons, which are made up of 4 different types of nitrogenous bases. Therefore, DNA is able provide enough unique codes for 4x4x4=64 different amino acids. However, only 20 types of amino acids exist, which indicates that 19/20 of those amino acids have at least more than 1 codon to encode it.For example; If the codon ACU mutated to ACC, how that that affect the protein?Well, it would not effect the protein at all, because both ACU and ACC encode the amino acid threonine.In addition, some amino acids have very similar properties to other amino acids. Even if amino acid X was replaced with amino acid Y, the effect on the protein may be small or non-existing if X and Y share similar properties.
