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Why does one DNA strand grow one nucleotide at a time and the other is assembled in short fragments?
Wiki User
∙ 13y ago
The two strands of parental DNA separate, and each becomes a template for the assembly of a complementary strand from a supply of Why_does_one_DNA_strand_grow_one_nucleotide_at_a_time_and_the_other_is_assembled_in_short_fragmentsnucleotides. The nucleotides line up one at a time along the template strand in accordance with base pairing rules. Enzymes link the nucleotides to form the new DNA strands.
Read more: Why_does_one_DNA_strand_grow_one_nucleotide_at_a_time_and_the_other_is_assembled_in_short_fragments
Wiki User
∙ 11y ago
Wiki User
∙ 13y agoThe two strands of parental DNA separate, and each becomes a template for the assembly of a complementary strand from a supply of free nucleotides. The nucleotides line up one at a time along the template strand in accordance with base pairing rules. Enzymes link the nucleotides to form the new DNA strands.
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What is lagging strand in replication of DNA?
The two strands of DNA in animal cells are arranged backwards to each other - the start of one is paired with the ending of the other. However, the enzyme that replicates DNA (DNA polymerase) can only work from start to finish. On one strand, DNA polymerase can work front to back in a continuous chain - the strand that allows this is called the leading strand because it "leads" in completion status. On the other strand, the DNA polymerase has to work backwards in pieces and then put the pieces back together into a single chain - the strand that causes this is called the lagging strand because it "lags behind" the other in completion status.
What is the definition of a lagging strand?
A lagging strand is one of two strands of DNA found at the replication fork, or junction, in the double helix; the other strand is called the leading strand. A lagging strand requires a slight delay before undergoing replication, and it must undergo replication discontinuously in small fragments.
Complementary dna sequence?
A complimentary DNA sequence is the genetic code on the partner strand that aligns with and corresponds to (matches) the code on the primary strand. Each nucleotide has a match, A matches T and C matches G, therefore the complimentary sequence for ATCGA is TAGCT.
What okazaki fragments are?
In DNA replication, the two DNA strands acting as templates need to be synthesized simultaneously. DNA polymerase is an enzyme which can synthesize the DNA only in 5' to 3' direction.the two template strands are anti-parallel to each other and their complementary strands are synthesized in different direction. In one of the strand DNA is synthesized continuously by adding nucleotides at 3'-OH end. this is referred as 'leading strand' synthesis. the other strand to be synthesized is replicated in short fragments referred 'Okazaki fragments' named after their discoverer Reiji Okazaki.
At each replication fork one new strand of DNA is made of many small pieces. what is the strand of DNA called?
When the two parent strands of DNA are separated to begin replication, one strand is oriented in the 5' to 3' direction while the other strand is oriented in the 3' to 5' direction. DNA replication, however, is inflexible: the enzyme that carries out the replication, DNA polymerase, only functions in the 5' to 3' direction. This characteristic of DNA polymerase means that the daughter strands synthesize through different methods, one adding nucleotides one by one in the direction of the replication fork, the other able to add nucleotides only in chunks. The first strand, which replicates nucleotides one by one is called the leading strand; the other strand, which replicates in chunks, is called the lagging strand. The lagging strand replicates in small segments, called Okazaki fragments. These fragments are stretches of 100 to 200 nucleotides in humans (1000 to 2000 in bacteria).
If you had a small single strand of DNA with the nucleotide sequence cagtact what would the sequence be for the other DNA strand?
gcgtatagtccg is the DNA compliment
What determines the nucleotide sequence of the newly synthesised strand during DNA replication?
It must be the mirror image of the original half strand. (and the other strand, which is the mirror of the first is making the mirror of the mirror ... the original !)
What DNA replication enzyme attaches okazaki fragments as a continuous strand of DNA?
Ligase joins okazaki fragments to each other to form a continuous strand of DNA
What is lagging strand in replication of DNA?
The two strands of DNA in animal cells are arranged backwards to each other - the start of one is paired with the ending of the other. However, the enzyme that replicates DNA (DNA polymerase) can only work from start to finish. On one strand, DNA polymerase can work front to back in a continuous chain - the strand that allows this is called the leading strand because it "leads" in completion status. On the other strand, the DNA polymerase has to work backwards in pieces and then put the pieces back together into a single chain - the strand that causes this is called the lagging strand because it "lags behind" the other in completion status.
What is the definition of a lagging strand?
A lagging strand is one of two strands of DNA found at the replication fork, or junction, in the double helix; the other strand is called the leading strand. A lagging strand requires a slight delay before undergoing replication, and it must undergo replication discontinuously in small fragments.
Complementary dna sequence?
A complimentary DNA sequence is the genetic code on the partner strand that aligns with and corresponds to (matches) the code on the primary strand. Each nucleotide has a match, A matches T and C matches G, therefore the complimentary sequence for ATCGA is TAGCT.
What okazaki fragments are?
In DNA replication, the two DNA strands acting as templates need to be synthesized simultaneously. DNA polymerase is an enzyme which can synthesize the DNA only in 5' to 3' direction.the two template strands are anti-parallel to each other and their complementary strands are synthesized in different direction. In one of the strand DNA is synthesized continuously by adding nucleotides at 3'-OH end. this is referred as 'leading strand' synthesis. the other strand to be synthesized is replicated in short fragments referred 'Okazaki fragments' named after their discoverer Reiji Okazaki.
At each replication fork one new strand of DNA is made of many small pieces. what is the strand of DNA called?
When the two parent strands of DNA are separated to begin replication, one strand is oriented in the 5' to 3' direction while the other strand is oriented in the 3' to 5' direction. DNA replication, however, is inflexible: the enzyme that carries out the replication, DNA polymerase, only functions in the 5' to 3' direction. This characteristic of DNA polymerase means that the daughter strands synthesize through different methods, one adding nucleotides one by one in the direction of the replication fork, the other able to add nucleotides only in chunks. The first strand, which replicates nucleotides one by one is called the leading strand; the other strand, which replicates in chunks, is called the lagging strand. The lagging strand replicates in small segments, called Okazaki fragments. These fragments are stretches of 100 to 200 nucleotides in humans (1000 to 2000 in bacteria).
Describe the significance of Okazaki fragments?
Okazaki fragments are created during DNA replication because DNA Polymerase can only add nucleotides in a 5' to 3' direction. This means that one strand (the leading strand) can be continuously created, but the other strand (the lagging strand) runs in the opposite direction. This means that loops must be created and shorter parts of DNA replicated one at a time. This creates fragments on the lagging strand. The RNA primers on this strand are later replaced with DNA by DNA Polymerase I, and joined together with DNA ligase.
Why is replication on one strand of DNA continuous while on the other strand the replication must be discontinuous?
New strands of DNA can only be created in one direction - 5' to 3'. This is because only the 3' end of the DNA is able to join to a new nucleotide. The two strands of DNA are antiparallel - meaning they run in different directions. Therefore only one strand (called the leading strand) is running in the correct direction for continuous replication. The other strand (called the lagging strand) must first be looped around so that small sections can be replicated in the correct direction.
How does DNA copy of itself?
DNA makes copies of itself through the process of replication. Because the nucleotide bases are complementary, they automatically make the other strand of complementary bases when the division of the cell occurs.
Why can't DNA polymerase synthesize a new strand of DNA without the help of a RNA primer?
Because DNA Polymerase requires the OH on the 3' as an active site. It uses the OH on the 3' end of a nucleotide to attach a phosphate from the 5' end of the next nucleotide. It only works in this direction, and that is why DNA polymerase works 5' to 3'.
