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Nothing. The enzyme is not changed by the process of lowering the activation energy of the reaction with the substrates.

In their active site some enzymes just give two substrates a protected area for a reaction, some stress bonds thus causing a reaction and some preform catabolically within their active site using their R groups.

Regardless of the enzymes activity it is not changed and goes on to perform many processes in the cell.

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Q: What happens to an enzyme when it performs its function what does this mean about enzyme molecules?
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