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Generally, if you're cooking under 3000 feet, a 2-4 oz piece of tilapia that is 1/4-3/4" thick can be cooked at 350 degrees for 30-35 minutes. If you're cooking at a higher altitude, you might want to increase the heat a bit and cook for less time so it doesn't get dry. For thicker pieces reduce the heat to 300 or 325 and increase the time. When you try for the first time, definitely start fresh, so that if it's slightly undercooked you aren't risking getting sick (which is rarely much of a concern). Preheat the oven to 325-350, depending on how good you are at watching it. Start checking the meat after about 20 minutes, checking the side and the middle. By now the side will be completely white and not at all transparent, and probably a bit flakey and the very edges will be starting to crisp/dry out a bit. Check the middle. If you like it "rare", it's probably about done. This is entirely to taste. Some people like fish totally cooked and dry, so you might want to keep it in another 10-15 minutes.
What else can I help you with?
How long do you bake talapia?
Since Talapia is a seafood, it is extremely important to know that overcooking of the fish should be avoided. When starting to cook baked Talapia see that the temperature of the oven is set to 300 degrees Fahrenheit to 400 degrees Fahrenheit and not exceed that. Coming to how long to bake Talapia, the recommended time would be 15-20 minutes if covered and if uncovered, it could extend to 30-40 minutes.
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