The rate-limiting step and the regulatory step are related concepts in metabolic pathways, but they are not the same. The rate-limiting step is the slowest reaction in a pathway, which determines the overall rate of the process. In contrast, a regulatory step refers to any step in a pathway that can be modulated by various factors, such as enzymes, allosteric regulators, or feedback mechanisms. While the rate-limiting step is often a regulatory step, not all regulatory steps are rate-limiting.
The rate-limiting step of an enzyme-catalyzed reaction is the slowest step in the reaction that determines the overall rate at which the reaction proceeds.
The HMG-CoA Reductase reaction is rate-limiting for cholesterol synthesis.
Phosphofructokinase (PFK)
Phosphofructokinase
The rate-limiting step of the Calvin Cycle in photosynthesis is significant because it controls the overall speed at which the cycle can produce glucose, which is essential for plant growth and energy storage. If this step is slow, it can limit the plant's ability to efficiently convert carbon dioxide into sugars, impacting its overall productivity.
A rate-governed or rate-limiting process is a process in which there are several steps; however, the rate of one or more steps is much slower than all the others. The rates of the previous steps and following steps are assuming to be infinite, and the rate of the process only depends on the rate-limiting step(s).
It inhibits the rate-limiting enzyme (HMG-CoA reductase) in the multi-step pathway of cholesterol synthesis, in the liver.
Chemical reactions involve the breaking and forming of bonds, and the rate at which this happens can vary widely. Some reactions, like rusting, can be very slow, taking years to noticeably occur. However, reactions can be sped up by changing conditions like temperature and pressure.
it is Carbamoyl phosphate synthase 1 which does the following:CO2 & NH3 -> Carbamoyl phosphatedon't forget the rate limiting enzyme is stimulated by N-acetylglutamate (NAG)
In the succinate-fumarate step, electrons are transferred from succinate to FAD to form FADH2, which eventually reduces quinone to quinol. This reduction reaction leads to a color change in DPIP, indicating the transfer of electrons from succinate to the electron transport chain.
To determine the rate-determining step from a graph, look for the slowest step where the rate of reaction is the lowest. This step will have the highest activation energy and will be the one that controls the overall rate of the reaction.