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The rate-limiting step in the conversion of fumarate to glutamate typically occurs during the enzyme-catalyzed reaction involving the enzyme glutamate synthase. This enzyme facilitates the incorporation of nitrogen into α-ketoglutarate to form glutamate, which is a key step in amino acid metabolism. Fumarate itself is an intermediate in the citric acid cycle, and its conversion to glutamate is not direct but involves several metabolic pathways, including the transamination process. Overall, the regulation of these reactions can be influenced by the availability of substrates and other factors in the cellular environment.
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Is rate limiting step and regulatory step same?
The rate-limiting step and the regulatory step are related concepts in metabolic pathways, but they are not the same. The rate-limiting step is the slowest reaction in a pathway, which determines the overall rate of the process. In contrast, a regulatory step refers to any step in a pathway that can be modulated by various factors, such as enzymes, allosteric regulators, or feedback mechanisms. While the rate-limiting step is often a regulatory step, not all regulatory steps are rate-limiting.
What is the rate-limiting step of an enzyme-catalyzed reaction?
The rate-limiting step of an enzyme-catalyzed reaction is the slowest step in the reaction that determines the overall rate at which the reaction proceeds.
Rate limiting step of cholesterol?
The HMG-CoA Reductase reaction is rate-limiting for cholesterol synthesis.
Which enzyme catalyzes the rate-limiting step of glycolysis?
Phosphofructokinase (PFK)
Which of the following enzymes catalyzes the rate-limiting step of glycolysis?
Phosphofructokinase
What is the significance of the rate-limiting step of the Calvin Cycle in photosynthesis?
The rate-limiting step of the Calvin Cycle in photosynthesis is significant because it controls the overall speed at which the cycle can produce glucose, which is essential for plant growth and energy storage. If this step is slow, it can limit the plant's ability to efficiently convert carbon dioxide into sugars, impacting its overall productivity.
What is a rate governed process in Chemical Engineering?
A rate-governed or rate-limiting process is a process in which there are several steps; however, the rate of one or more steps is much slower than all the others. The rates of the previous steps and following steps are assuming to be infinite, and the rate of the process only depends on the rate-limiting step(s).
How does Lipitor work?
It inhibits the rate-limiting enzyme (HMG-CoA reductase) in the multi-step pathway of cholesterol synthesis, in the liver.
What is the slowest chemical reaction?
Chemical reactions involve the breaking and forming of bonds, and the rate at which this happens can vary widely. Some reactions, like rusting, can be very slow, taking years to noticeably occur. However, reactions can be sped up by changing conditions like temperature and pressure.
What is the rate limiting enzyme of the urea cycle?
it is Carbamoyl phosphate synthase 1 which does the following:CO2 & NH3 -> Carbamoyl phosphatedon't forget the rate limiting enzyme is stimulated by N-acetylglutamate (NAG)
How do you know that the electrons causing the change in color of dpip are involved in the succinate fumarate step?
In the succinate-fumarate step, electrons are transferred from succinate to FAD to form FADH2, which eventually reduces quinone to quinol. This reduction reaction leads to a color change in DPIP, indicating the transfer of electrons from succinate to the electron transport chain.
How to determine the rate determining step from a graph?
To determine the rate-determining step from a graph, look for the slowest step where the rate of reaction is the lowest. This step will have the highest activation energy and will be the one that controls the overall rate of the reaction.
