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Inactivation gates of voltage-gated Na+ channels close, while activation gates of voltage-gated K+ channels open.

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What is depolarization of a neurotransmitter?

Depolarization of a neurotransmitter refers to the shift in the electrical charge of the neuron, making it more likely to generate an action potential. This can occur when a neurotransmitter binds to its receptor on the postsynaptic membrane, causing ion channels to open and allowing the influx of positively charged ions. This depolarization triggers a series of events that lead to the transmission of the nerve signal.


What effect of the action potential if sodium channels are kept closed?

The action potential will not generate if the sodium channels are kept closed.This is because the sodium channels are responsible for the dramatic rising phase of membrane depolarization that occurs when the threshold of activation is reached. As a membrane potential gradually depolarizes (which can occur for a variety of reasons such as neurotransmitter stimulation, mechanical deformation of the membrane, etc), that membrane potential gradually comes closer to that threshold of activation. Once that threshold is reached, the voltage gated sodium channels open and allow for a dramatic influx of sodium ions into the cell. This results in a rapid depolarization which is seen as the rising phase of that upward spike noted in an action potential. Without the ability to open these sodium channels we may reach the threshold of activation, but the actual action potential will not occur.


What changes occur in the neuron?

In response to stimuli, neurons may undergo changes in their membrane potential, leading to the generation and propagation of electrical impulses called action potentials. Additionally, synaptic connections between neurons can be strengthened or weakened through processes like long-term potentiation and depression, which play a role in learning and memory.


Why don't the terms depolarization and action potential mean the same thing?

Depolarization occurs when a stimulus opens sodium channels which allow more sodium to go into the membrane making it less negative and more positive (toward reaching threshold). An action potential can only occur once the membrane reaches threshold which means it has reached the level needed through depolarization. An action potential is a brief reversal in polarity of the membrane making the inside more positive and the outside more negative, the reverse occurs again once the membrane reaches resting potential.


What cell structure is used to prepare for depolarization?

The cell structure used to prepare for depolarization is the sodium-potassium pump, which actively transports sodium out of the cell and potassium into the cell to establish the necessary concentration gradients for depolarization to occur.


When does arterial depolarization occur?

Arterial depolarization occurs when action potentials are generated in the cardiac cells of the heart during the electrical conduction system, leading to the contraction of the heart muscle. This depolarization occurs as the electrical signal travels through the atria and then the ventricles, causing them to contract and pump blood.


How are local and action potentials similar?

Local and action potentials both involve changes in membrane potential due to the movement of ions across the cell membrane. They both follow the same basic principles of depolarization and repolarization. However, action potentials occur in excitable cells like neurons and muscle cells, while local potentials are smaller, graded changes in membrane potential that occur in non-excitable cells.


What changes occur in capacitation?

During capacitation, changes occur in the sperm's membrane, including an increase in membrane fluidity and alterations in ion channels. There is also an increase in intracellular calcium levels, which triggers signaling pathways required for the acrosome reaction. Additionally, capacitation leads to an increase in sperm motility and the ability to bind to the zona pellucida of the egg.


What are reflections that occur at changes in impedance?

Return loss refers to the reflections that occur at changes in impedance.


A virus causes damage to the sodium channels of the postsynaptic neuron such that they open very slowly in response to a neurotransmitter How does this modify the generation of an action potential?

This modification would likely result in a delayed or weakened depolarization of the postsynaptic neuron membrane. As a consequence, the generation of an action potential may be slower or fail to reach the threshold needed to trigger an action potential, leading to impaired signal transmission between neurons.


What changes occur in the neuron during an action potential?

During an action potential, the neuron undergoes a rapid change in membrane potential as sodium ions rush into the cell, leading to depolarization. Subsequently, potassium ions move out of the cell, repolarizing the membrane back to its resting state. This rapid change in membrane potential allows for the transmission of electrical signals along the neuron.


What is the function of chromosome changes that occur in mitosis?

These changes usually occur in meiosis not mitosis. It causes a mixing of the alleles.