Well for people who aren't familiar with the abbr. Nicotinamide adenine dinucleotide aka NAD acts as an electron and hydrogen carriers in some oxidation-reduction reactions in the Krebs Cycle, and flavin adenine dinucleotide aka FAD is a hydrogen acceptor molecule in the Krebs Cycle.
A. Transfer electrons to NAD+ B. Power Krebs cycle C. Receive electrons from NADH D. Produce ATP from sugar
Loss of electrons causes NADH to become NAD+. This cycle of oxidation reduction helps generate ATP in cell respiration.
Alcoholic fermentation occurs in organisms such as yeast, as produces ethyl alcohol. Lactic acid fermentation occurs in animals such as humans and produces lactic acid instead of alcohol.
This is the Glycolysis pathway Glycolysis (the breakdown of glucose to pyruvate and lactate, occurs in the cell cytoplasm): Glucose + 2 ATP + 4 ADP + 2 NAD -> 2 Pyruvate + 2 ADP + 4 ATP + 2 NADH + energy. Oxidation of glucose is known as glycolysis. Glucose is oxidized to either lactate or pyruvate. Under aerobic conditions, the dominant product in most tissues is pyruvate and the pathway is known as aerobic glycolysis. When oxygen is depleted, as for instance during prolonged vigorous exercise, the dominant glycolytic product in many tissues is lactate and the process is known as anaerobic glycolysis. "These studies demonstrate that orderly glycolysis in the erythrocyte is regulated by the NAD-to-NADH ratio and also provide a method that makes possible the in vitro study of erythrocyte glycolysis." The conversion of pyruvate to lactate, under anaerobic conditions, provides the cell with a mechanism for the oxidation of NADH (produced during the G3PDH reaction) to NAD which occurs during the LDH catalyzed reaction. This reduction is required since NAD is a necessary substrate for G3PDH, without which glycolysis will cease. Normally, during aerobic glycolysis the electrons of cytoplasmic NADH are transferred to mitochondrial carriers of the oxidative phosphorylation pathway generating a continuous pool of cytoplasmic NAD NADH
It's called the Krebs's cycle and it consists of the steps to convert a 2 carbon sugar into CO2 and H2O. (And you don't own the genetic code to do this ... only the mitochondria do.)
NAD and FAD are reduced in the Krebs cycle and oxidised in the electron transport chain.
Because NAD+ level will decrease if oxygen is not present to regenerate NADH to NAD + Because NAD+ level will decrease if oxygen is not present to regenerate NADH to NAD +
They form FADH2 and NADH
In the Krebs cycle NAD+ is reduced to NADH. This is one of the electron carriers. Also FAD is reduced to FADH2 which is the other electron carrier produced during the Krebs cycle.
The intermediate electron acceptor for oxidations in both glycolysis and the Krebs cycle is NAD+ (nicotinamide adenine dinucleotide). NAD+ accepts electrons and becomes reduced to NADH during these metabolic pathways. NADH can then donate its electrons to the electron transport chain for further energy production.
The products of the Krebs Cycle are ATP, NADH, FADH2, and carbon dioxide. The reactants are acetyl-CoA, NAD+, FAD, and ADP. The Krebs Cycle takes place in the mitochondrial matrix of eukaryotic cells.
In the Krebs cycle, a total of 3 molecules of NADH are produced.
The step of the Krebs cycle that requires both NAD and ADP as reactants is the conversion of isocitrate to alpha-ketoglutarate, catalyzed by isocitrate dehydrogenase. NADH and ATP are produced in this step.
The Krebs cycle, or citric acid cycle, produces 4 NADH electron carriers and carbon dioxide. Other products include FADH2 and ATP.
# ATP (Adenosine Triphosphate) # NADH (a combination of NAD+ and H+) # FADH2 (a combination of FAD+ and 2H+)
NADH
The electron carrier molecules of the Krebs cycle are NADH and FADH2. In the Calvin cycle, the electron carrier molecule is NADPH.