Carnitine is synthesized from the amino acid lysine. The first enzyme in the biosynthesis, N-trimethyllysine hydroxylase, is most concentrated in the mitochondria of kidneys and liver tissue. The full pathway is mentioned in the Clin Chem reference in graphical form (nice).
From the JBC article:
In the carnitine biosynthetic pathway, trimethyllysine is first hydroxylated at the beta position by epsilon-trimethyllysine hydroxylase (TMLH1), after
which the resulting epsilon-hydroxytrimethyllysine is cleaved by a
specific aldolase into -trimethylaminobutyraldehyde and glycine
(6, 8). Subsequently, -trimethylaminobutyraldehyde is
oxidized by -trimethylaminobutyraldehyde dehydrogenase to
form -butyrobetaine (9). In the last step, -butyrobetaine is
hydroxylated at the -position by a second hydroxylase, -butyrobetaine
hydroxylase, yielding L-carnitine
Also see http://www.answers.com/carnitine
The classical complement pathway is a group of proteins that arrange the antibody response when you are sick. So basically they will spring into action when something is not right in your body.
Vitamin D is not synthesized in the body when a person is confined to a dark cell for a long time. However, it can be obtained through diet or supplements. Vitamin D is primarily synthesized in the skin in response to sunlight exposure, so lack of sunlight would hinder its natural production in the body.
our body cam make protein in the form of amino acid there are twenty amino acid in which all can be synthesized but in the twenty 10 amino acid is synthesized by simple process and the other 10 takes a long process so that they shouled be taken by diet
The L-Carnitine diet refers to a dietary approach that incorporates L-Carnitine supplementation as a means to support weight loss efforts. L-Carnitine is a naturally occurring compound in the body that plays a crucial role in energy metabolism. It helps transport fatty acids into the mitochondria, where they are converted into energy. The idea behind the L-Carnitine diet is that by increasing L-Carnitine levels through supplementation, the body's ability to utilize stored fat for energy can be enhanced, potentially leading to weight loss. While L-Carnitine supplement has been studied for its potential benefits in weight loss, the results have been mixed. Some studies have shown positive effects, indicating that L-Carnitine can enhance fat oxidation and support weight loss efforts. However, other studies have not found significant weight loss benefits with L-Carnitine supplementation alone. It's important to note that the effectiveness of the L-Carnitine diet may vary among individuals. Factors such as overall diet, exercise routine, and individual metabolism can influence the outcomes. Additionally, incorporating L-Carnitine into a well-rounded weight loss plan that includes a balanced diet and regular exercise is generally more effective than relying solely on L-Carnitine supplementation. To determine whether the L-Carnitine diet works for you, it's recommended to consult with a healthcare professional or a registered dietitian. They can evaluate your individual needs, goals, and health status to provide personalized recommendations. It's also crucial to consider that no single dietary approach or supplement guarantees weight loss. Sustainable weight loss requires a comprehensive lifestyle change, including a balanced and nutritious diet, regular physical activity, proper hydration, and adequate sleep. Remember, before starting any new diet or supplementation regimen, it's essential to consult with a healthcare professional to ensure it aligns with your specific needs and to monitor your progress along the way. If you want to search out perfect supplement that help in your diet plan. So We have a wide range of Liquid L-Carnitine Supplements. Check out the L-Carnitine Collection from HealthFarm Nutrition Website
i dont know the answer to this question so that is why i am asking you for your help on this question or you can come up with an answer for this question so that i can get the answer
L-carnitine is generally considered safe to take with simvastatin, but it's always best to consult with a healthcare provider before combining supplements with medications. Some studies suggest that L-carnitine may help mitigate certain side effects of statins, such as muscle pain. However, individual responses can vary, so professional guidance is important to ensure safety and efficacy.
Unfortunately, L-carnitine come mostly in animal products. It is commonly found in beef, pork, milk, chicken, fish, eggs, and cheese. Still, L-carnitine can be found in some vegen foods. Those are avocado, asparagus, bread, cooked rice, and orange juice. While it is not as abundant (beef is 95 mg per serving, while per serving avocados are 2 mg and rice is 0.0449 mg), L-carnitine can still be found in vegen foods. Even so, it is still good to take a vitamin that contains some L-catnitine in it just to help.
it keeps your blood pressure flowing in your body so you don't die. Aside from This, the blood vessels are also the pathway of the blood towards the important organs of the body, this responsible for the ultimate functioning of the organs. Without them, the body organs will not be able to receive blood that oxygenates them.
there's a problem ,or there's a pathway that have a problem in your brain .So the circulation of blood stops,and when the other part of the body ,could that receive the blood,theres a possibility that you are going to ba stroke.
>Dietary support for weight lossDietary Supplements for Weight LossLosing weight can be extremely difficult, but fortunately there are a number of dietary supplements available that can help speed up the process in a way that also supports your overall health.L-CarnitineL-Carnitine is a substance your body uses to burn fatty acids for the generation of energy. It is often used as a nutritional supplement to provide an energy lift and burn fat. Most cells have mitochondria- tiny furnaces that burn fuel for your body. L-Carnitine helps transport fat to the mitochondria so it can be used as fuel. It is not a "magic bullet", however- it must be used in conjunction with sensible eating to get the most benefit.Your own body is able to manufacture limited amounts of L-Carnitine using the amino acids methionine and lysine, as well as vitamins like B6, niacin, and vitamin C. However, any deficiency in these nutrients can result in lower production of carnitine, and the lowered energy levels and fat burning that result from the deficiency.You can also get your requirements for L-Carnitine in the foods you eat. It is found primarily in meat and animal products. Sources include red meat, turkey, and chicken. Dairy products also contain small amounts. Most fruits and veggies contain little carnitine, with the exception of avocados and tempah.Lipoic AcidIncreasing your energy levels with L-Carnitine is important, but so is preventing some of the negative effects created at the cellular level. As each cell burns fat, it also can create oxidative stress that damages cells. Lipoic acid is known as the "antioxidant's antioxidant". Antioxidants help neutralize molecules known as "free radicals" that can damage healthy cells and tissue. Taken in conjunction with L-Carnitine, lipoic acid helps antioxidants regenerate as they protect cells, in addition to being a potent antioxidant in its own right.FiberIf you are looking to lose weight, getting more fiber into your diet is very important. A meal with fiber makes your stomach feel full longer and assists in digestion. Good sources are apples, nuts, and beans.
Circuit
Bring me some cement so I can finish building this pathway.