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A receptor potential and an excitatory postsynaptic potential (EPSP) are both graded potentials that result from the opening of ion channels in response to a stimulus. In receptor potentials, sensory receptors respond to external stimuli, leading to depolarization, while EPSPs occur when neurotransmitters bind to receptors on the postsynaptic membrane, allowing positively charged ions to flow in. Both processes can summate, contributing to the generation of action potentials if the depolarization reaches a threshold. Thus, they share mechanisms of synaptic transmission and signal transduction in the nervous system.

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1mo ago

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How does synaptic integration determine if a nerve impulse is generated or not generated in a neuron?

Neurons integrate incoming signals and sum up the excitatory and inhibitory signals, integration. The excitatory neurotransmitter produces a potential change (signal). This signal pushes the neuron closer to an action potential. If the neuron receives excitatory signals chances are that the axon will transmit a nerve impulse. The inhibitory neurotransmitter produces signals that drive neurons further from an action potential. If neurons receive both the inhibitory and the excitatory signals the summing of the signals may prohibit the axon from firing.


What determines if an action potential is initiated in the postsynaptic neuron?

Every time neurotransmitter is released from the presynaptic neuron it generates an excitatory post synaptic potential(EPSP) in the postsynaptic neuron. When the EPSP is greater than the threshold for excitation an action potential is generated.


What is synaptic potential?

A synaptic potential is a change in the electrical potential of a neuron in response to the release of neurotransmitters at a synapse. It can be either excitatory, causing depolarization and promoting action potential firing, or inhibitory, causing hyperpolarization and reducing the likelihood of action potential firing. These changes in potential are essential for communication between neurons in the brain.


What ion is the cause of excitatory post-synaptic potential?

The cause of excitatory post-synaptic potentials is the influx of sodium ions into the postsynaptic neuron. This influx of positive charge depolarizes the neuron, making it more likely to generate an action potential.


How exitatory and inhibitory interact in normal nerve function?

Excitatory and inhibitory signals work together in normal nerve function to maintain balance and regulate the firing of neurons. Excitatory signals stimulate a neuron to fire an action potential, while inhibitory signals prevent or reduce the likelihood of an action potential being generated. This balance is crucial for proper information processing and nerve function in the body.


When neurotransmitters bind to or attach to receptor sites the probability of the postsynaptic neuron firing an action potential?

... Depends entirely on the post-synaptic neuron. If it is an inhibitory synapse (often located on the actual body of the dendrite or soma), then the probability of that post-synaptic neuron firing DECREASES. The reverse is true if it is excitatory; the synapse (more likely located on a dendritic spine) will more likely induce the post-synaptic neuron to fire an action potential.


What is the difference between AP and EP?

AP (Action Potential) and EP (Excitatory Post-synaptic Potential) are both electrical signals in neurons, but they serve different functions. An action potential is a rapid, all-or-nothing signal that travels along the neuron’s axon, allowing for long-distance communication. In contrast, an excitatory post-synaptic potential is a graded potential that occurs in the dendrites and soma of a neuron, resulting from synaptic transmission and leading to depolarization; it may contribute to reaching the threshold for an action potential but does not propagate along the axon.


What is the difference between action potentials and synaptic potentials?

A synaptic potential exists at the INPUT of a neuron (dendrite), and an action potential occurs at the OUTPUT of a neuron (axon). (from OldGuy)(from Ilantoren:) A synaptic potential is the result of many excitatory post synaptic potentials (epsp) each one caused by the synaptic vesicles released by the pre-synaptic terminus. If there are enough of these epsp then the responses will summate and depolarize the post-synaptic membrane at the axon hillock enough to fire an action potential.


What is a sub-threshold change in membrane potential within the cell body that decays as it travels away from its point of origin?

A sub-threshold change in membrane potential in the cell body, such as an excitatory post-synaptic potential (EPSP), does not reach the threshold for action potential initiation. As it travels along the dendrites and cell body, it decays and dissipates, failing to trigger an action potential. This phenomenon is crucial in the integration of signals by neurons.


How can decision-making in the CNS result from the interaction between the activities of excitatory and inhibitory presynaptic neurons at synapses?

During decision-making, information is processed to choose between two or more alternatives. This involves the interaction of excitatory and inhibitory neurons. This process also involves excitatory and inhibitory neurotransmitters. The post-synaptic action potential is determined by the sum of all signals.


What is local graded potential?

Local graded potentials are small changes in membrane potential that occur in response to neurotransmitter binding to ligand-gated ion channels on the post-synaptic neuron. These potentials can summate and affect the likelihood that an action potential will be generated in the neuron. They are also referred to as synaptic potentials.


What forms receptor sites on the post synaptic cell membrane?

Protein molecules on the post-synaptic cell membrane form receptor sites that bind with neurotransmitters released from the pre-synaptic neuron. This binding triggers downstream signaling pathways within the post-synaptic cell, leading to various cellular responses.