heme
Hemoglobin SS disease (Hb SS)
Hemoglobin.
Sickle cell disease is caused by a mutation in the gene that encodes for hemoglobin, a protein in red blood cells that carries oxygen. This mutation results in the production of abnormal hemoglobin known as hemoglobin S, which causes red blood cells to become sickle-shaped and less flexible.
Hemoglobin
It is Hemoglobin
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SS sickle disease, or sickle cell anemia, is a genetic blood disorder characterized by the presence of abnormal hemoglobin, known as hemoglobin S. This leads to the distortion of red blood cells into a sickle shape, causing blockages in blood vessels, pain crises, and various complications. SC sickle disease occurs when an individual inherits one sickle cell gene (hemoglobin S) and one gene for hemoglobin C. While SC disease is generally milder than SS disease, it can still result in similar health issues.
Carriers of sickle cell disease, known as sickle cell trait, typically do not experience symptoms of the disease. They usually have one normal hemoglobin gene and one sickle hemoglobin gene, which means they can produce both normal and abnormal hemoglobin. While they are generally asymptomatic, under extreme conditions such as high altitude or severe dehydration, some carriers may experience mild symptoms. However, they do not have the full-blown disease, which primarily affects individuals with two sickle hemoglobin genes.
There are several types of sickle cell disease, including sickle cell anemia, sickle beta thalassemia, and sickle cell-hemoglobin C disease. These types differ based on the specific genetic mutations that affect the hemoglobin protein in red blood cells. Sickle cell anemia is the most common and severe form, where individuals have two copies of the sickle cell gene. Sickle beta thalassemia and sickle cell-hemoglobin C disease are milder forms that result from different combinations of genetic mutations. Symptoms and complications can vary among the different types of sickle cell disease.
Sickle cell disease is a mutation in the gene that codes for hemoglobin, which causes the hemoglobin and the cell to become elongated and look like a sickle rather than its normal disc shape.
Sickle Cell disease A disease that involves misshaped cells that can easily cause blood clots.
Not containing enough Red blood cells. From African and Indian decent. Sickle cell disease is a defective hemoglobin.