Yes, the rough strain of Pneumococcus, specifically Streptococcus pneumoniae, can act as a pathogen. While the smooth strain is typically virulent due to its polysaccharide capsule, the rough variant lacks this capsule and is generally considered less virulent. However, under certain conditions or in immunocompromised individuals, even the rough strain can contribute to disease. Its pathogenic potential may also depend on other factors, such as genetic mutations or co-infections.
A very important characteristic about bacteria actually created live S-strain to exist in the dead injected mouse. Bacteria is competent, in biological terms, meaning that cells can take up "naked" DNA from it's environment. Knowing that fact, when the heat-killed S-strain pneumoccus mixed with the live R-strain, the R-strain took in the DNA, therefore inheriting the deadly coating of the S-strain. So the R became S, and killed the mouse.
The process of transforming rough strain bacteria into smooth strain cells involves transferring genetic material - specifically a capsule gene - from a smooth strain to the rough strain. This genetic transfer results in the expression of a protective capsule on the surface of the rough strain cells, converting them into smooth strain cells with enhanced virulence.
SARS is not a pathogen, it is an syndrome similar to AIDS. It is caused by a virus called coronavirus, but it is the mutated strain.
The rough strain of bacteria is non-virulent and does not cause disease, while the smooth strain is virulent due to its protective capsule. When the heat-killed smooth strain was introduced to the mice, it released its genetic material, which could be taken up by the rough strain through a process called transformation. This allowed the rough strain to acquire the virulence factors from the smooth strain, making it capable of causing disease and ultimately killing the mice. This phenomenon demonstrated the principle of bacterial transformation and the transfer of genetic traits.
The unexpected result was that the previously harmless rough strain bacteria were able to take up genetic material from the heat-killed smooth strain bacteria, becoming virulent. This demonstrated the concept of bacterial transformation and laid the foundation for understanding DNA as the genetic material.
t He then took the R strain (rough strain) and injected it into the mice and found that they did not contract the pneumonia illness and survived the insertion of the strain
he discovered pneumococcus
Pneumonia is a medical illness (an infection of the lungs) caused by a variety of pathogens (bacteria, viruses, fungi). Pneumococcus (full name Streptococcus Pneumoniae) is a bacteria and a common cause of pneumonia. Therefore vaccination against Pneumococcus will prevent some, but not all pneumonias.
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Benjamin White has written: 'The biology of pneumococcus' -- subject- s -: Accessible book, Bibliography, Immunity, Pneumococcus, Streptococcus pneumoniae
Pneumococcus pneumonie
The disease-causing strain of bacteria grew into smooth colonies on culture plates, whereas the harmless strain produced with rough edges.