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Acetylcholine is released at the neuromuscular junction and binds to a nicotinic receptor, causing an action potential to fire down the T tubules. The voltage change from this is sensed by the Sarcoplasmic Reticulum which then releases Ca2+ ions into the cytosol. The Ca2+ ions bind to troponin which moves tropomyosin from the active sites of the actin filament. Once the active sites are revealed, myosin quickly forms a cross bridge and begins contraction.

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What does ach do at a neuromuscular junction?

ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.


What is the neurotransmitter released at the motor end plate?

Acetylcholine is the primary neurotransmitter released at the motor end plate, where it binds to receptors on muscle cells to initiate muscle contraction.


The chemical that transmits the signal across the neuromuscular junction is called?

Acetylcholine is the chemical that transmits signals across the neuromuscular junction. It binds to receptors on the muscle cell membrane, leading to muscle contraction.


The two neurotransmitters that affect smooth muscle cells are acetylcholine and?

norepinephrine. Acetylcholine mainly causes smooth muscle contraction, while norepinephrine can either cause contraction or relaxation depending on the type of receptor it binds to on the smooth muscle cell.


Chemical released to stimulate muscle contraction?

Acetylcholine is the primary neurotransmitter released by motor neurons at the neuromuscular junction to stimulate muscle contraction. It binds to receptors on the muscle cell membrane, initiating a series of events that ultimately lead to muscle contraction.


What is the neurotransmitter used at the neuro muscular junction is?

The neurotransmitter used at the neuromuscular junction is acetylcholine. It is released from the motor neuron terminals and binds to receptors on the muscle cell membrane, leading to muscle contraction.


What chemical binds to the muscle cell memebrane causing a temporary rush of what into the muscle cell?

Acetylcholine binds to the muscle cell membrane, causing a temporary rush of calcium ions into the muscle cell. This influx of calcium triggers muscle contraction.


What is the chemical transmitter released at the neuromuscular junction?

Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.


What neurotransmitter neuron to muscle cell?

The neurotransmitter acetylcholine is released from neuron axon terminals and binds to nicotinic receptors on muscle cells, triggering muscle contraction.


Which neurotransmitter receptor is present on the sarcolemma?

Acetylcholine receptor is present on the sarcolemma of the muscle cells. This receptor is responsible for transmitting the signal to initiate muscle contraction when acetylcholine binds to it at the neuromuscular junction.


Describe the interaction of acetylcholine and calcium ions in stimulating muscle contraction?

The acetylcholine diffuses across the synapse and binds to and activates nicotinic acetylcholine receptors on the motor end plate of the muscle cell. Activation of the nicotinic receptor opens its intrinsic sodium/potassium channel, causing sodium to rush in and potassium to trickle out.


Neurotransmitter substance released at motor end plates by the motor neuron?

The neurotransmitter released at motor end plates by motor neurons is acetylcholine. It binds to receptors on the muscle cell membrane, leading to muscle contraction.