IgM
Yes, antigen presenting cells have major histocompatibility complex class I molecules.
two
Yes, Th2 cells activate B cells with mostly cytokines IL-4, IL-5, IL-10. Some B cells can activate without the help of Th2 cells, however, there are certain requirements for this such as repeated epitope.
IgG antibodies account for the bulk of circulating antibodies in the blood. They are the most abundant class of antibodies and play a crucial role in providing long-term immunity.
Presented by APCs as MHC-exogenous peptide complex
IgM is the class of antibody first secreted in response to a new antigen. It is produced during the initial immune response and helps to activate other components of the immune system.
Each antibody has a variable region at the top of the arms of the Y-Shaped structure of the antibody. These variable regions each have a different sequence of amino acids and therefore a different structure. This means that only specific antigens can bind to the binding sites - only those with a complementary shape. The antigen fits into the binding site by induced fit. Once the antigen has bound to the antibody it forms a highly specific antigen-antibody complex. Therefore the role of the variable region is to produce a specific binding site for each type of antigen.
CD8+ T lymphocytes, also known as cytotoxic T cells, become cytotoxic when they are activated by presenting antigens on major histocompatibility complex class I molecules. These cells play a key role in the immune response by directly killing infected or abnormal cells.
Lymphocytes are part of the human body's innate immune system. Natural killer cells seek out and destroy foreign cells by distinguishing surface molecules of major histocompatibility complex class.
On B-cell activation by antigen, it proliferates into antibody secreting plasma cells and memory cells. Plasma cells function in adaptive immunity. Specific secreted antibodies by plasma cells then bind to extracellular microbes, block their ability to infect host cells and promote their ingestion and subsequent destruction by phagocytes.
Presented by APCs as MHC-exogenous peptide complex
Antibodies are produced by B lymphocytes. An antibody is a class of proteins produced by B lymphocytes, sometimes known as B cells. To neutralize diseases or foreign substances like poisons, these antibodies bind to them. For instance, an antibody can attach to a virus, preventing it from infecting a healthy cell and spreading. B cells can enlist the aid of other cells in the fight against an infected cell. Central BioHub offers thousands of B cells collected from patients and healthy donors for research. Hurry up, order online.