That depends entirely upon the receptor that norepinephrine activates.
smooth muscle
Smooth Muscle Cells
norepinephrine. Acetylcholine mainly causes smooth muscle contraction, while norepinephrine can either cause contraction or relaxation depending on the type of receptor it binds to on the smooth muscle cell.
Acetylcholine and norepinephrine both affect smooth muscle contraction. They stimulate contraction in some muscles and inhibits contraction in others.
specific cardiac and smooth muscle fibers
It varies: In the somatic system (skeletal muscle) and parasympathetic branch of the autonomous nervous system (smooth & cardiac muscle) it is usually acetylcholine. In the sympathetic branch of the autonomous nervous system (smooth & cardiac muscle) it is usually norepinephrine (also called noradrenaline). There are exceptions, but this is the general rule.
Norepinephrine.
Increased sympathetic tone leads to the release of norepinephrine, which binds to alpha-1 adrenergic receptors on arteriolar smooth muscle. This binding initiates a signaling cascade that ultimately results in the relaxation of the smooth muscle, causing the arterioles to dilate.
smooth musclesmooth muscle
Smooth muscle
Sympathetic activation causes blood vessels to constrict by releasing a neurotransmitter called norepinephrine, which binds to receptors on the smooth muscle cells of the blood vessels. This binding triggers a series of events that ultimately lead to the contraction of the smooth muscle, resulting in the narrowing of the blood vessels.
SmoothI'm POSITIVE it's the Skeletal Muscle!