What is symptoms for sickle cell disease?

Answer 1

SymptomsSymptoms usually don't occur until after age 4 months.

Almost all patients with sickle cell anemia have painful episodes (crises), which can last from hours to days. These crises can affect the bones of the back, the long bones, and the chest.

Some patients have one episode every few years. Others have many episodes per year. The crises can be severe enough to require a hospital stay.

Common symptoms include:

• Attacks of abdominal pain
• Bone pain
• Breathlessness
• Delayed growth and puberty
• Fatigue
• Fever
• Jaundice
• Paleness
• Rapid heart rate
• Ulcers on the lower legs (in adolescents and adults)

Other symptoms include:

• Chest pain
• Excessive thirst
• Frequent urination
• Painful and prolonged erection (priapism - occurs in 10 - 40% of men with the disease)
• Poor eyesight/blindness
• Strokes
• Skin ulcers

Answer 2

The signs and symptoms of sickle cell anemia are different in each person. Some people have mild symptoms. Others have very severe symptoms and are often hospitalized for treatment. The main symptoms of sickle cell anemia are: Shortness of breath, dizziness, headache, colness in the hands and feet, pale skin and chest pain.

Although sickle cell anemia is present at birth, many infants don't show any signs until after 4 months of age. The most common signs and symptoms are linked to anemia and pain. Other signs and symptoms are linked to some of the complications of the condition.

Symptoms of Sickle Cell? There are many symptoms for sickle cell. Individuals with sickle cell may not experience all of these symptoms. The symptoms include: family history of sickle cell anemia, fatigue, breathlessness, rapid heart rate, delayed growth and puberty, susceptibility to infections ulcers on the lower legs (in adolescents and adults) jaundice, attacks of abdominal pain, weakness, joint pain, fever, vomiting, bloody (hematuria) urination, excessive thirst, excessive penis pain, priapism, chest pain and decreased fertility. Symptoms may not appear until 4 months after birth and are most severe during an acute episode.

Answer 3

The signs and symptoms of sickle cell anemia are different in each person. Some people have mild symptoms. Others have very severe symptoms and are often hospitalized for treatment. Although sickle cell anemia is present at birth, many infants don't show any signs until after 4 months of age. The most common signs and symptoms are linked to anemia and pain. Other signs and symptoms are linked to some of the complications of the condition. The general signs and symptoms of anemia are fatigue (tiredness), pale skin and nail beds, jaundice (yellowing of the skin and eyes), and shortness of breath. Sudden episodes of pain throughout the body are a common symptom of sickle cell anemia and are often referred to as "sickle cell crises." A sickle cell crisis occurs when the red blood cells sickle (become "C" shaped) and stick together in clumps. The clumps block the flow of blood through the small blood vessels (capillaries) in the limbs and organs. Sickle crises can cause acute or chronic pain. Acute pain is the most common type. This is sudden pain that can range from mild to very severe. The pain usually lasts from hours to a few days. Chronic pain usually lasts for weeks to months. Chronic pain can be hard to bear and mentally draining. This pain may severely limit daily activities. Almost all people with sickle cell anemia have painful crises at some point in their lives. Some have a crisis less than once a year. Others may have 15 or more crises in a year. Many factors can contribute to a sickle cell crisis. Often, more than one factor is involved and the exact cause can't be identified. Factors that occur in your body and aren't under your control can cause a sickle cell crisis, such as an infection. Factors that you can control also can affect whether you have a sickle cell crisis. For example, dehydration (when your body doesn't have enough fluid) can increase your chances of having a sickle cell crisis. Drinking plenty of fluids so your body is hydrated can often help decrease the chance of a crisis. The most common sites affected by sickle cell crises are the bones, lungs, abdomen, and joints. The blocked blood flow can cause pain and organ damage.

(http://www.nhlbi.nih.gov/health/dci/Diseases/Sca/SCA_SignsAndSymptoms.html) Symptoms of Sickle Cell? There are many symptoms for sickle cell. Individuals with sickle cell may not experience all of these symptoms. The symptoms include: family history of sickle cell anemia, fatigue, breathlessness, rapid heart rate, delayed growth and puberty, susceptibility to infections ulcers on the lower legs (in adolescents and adults) jaundice, attacks of abdominal pain, weakness, joint pain, fever, vomiting, bloody (hematuria) urination, excessive thirst, excessive penis pain, priapism, chest pain and decreased fertility. Symptoms may not appear until 4 months after birth and are most severe during an acute episode. Is Sickle Cell Found only in African Americans? No. Although African Americans have a high occurence of Sickle Cell, many other nationalities suffer from the disease. (http://www.mamashealth.com/sickle_cell.asp)

Answer 4

In a heterozygous condition (Hb S-A) the disease is much milder or asymptomatic and is called sickle cell trait.

Lab diagnosis of sickle cell is based on three observations

1 sickling of red cells under deoxygeneted conditions.

2 precipitation of hb S in a special medium.

3 hb electrophoresis.

Answer 5

Sickle cell is the name for a collective group of inherited autosomal recessive disorders, caused by an abnormal form of haemoglobin.

The most common signs and symptoms are linked to anaemiaand pain. Other signs and symptoms are linked to the disease's complications.

A person with a sickle cell gene from one parent will be a carrier of the disease, but a person with 2 genes, one from each parent, will have the disease.

The signs of sickle cell disease [SCD] vary greatly from person to person. Some people have mild symptoms. Others have very severe symptoms and often are hospitalized for treatment.

Many people with sickle cell anaemia are in reasonably good health most of the time. However, they may have chronic health problems and pain because of organ tissue hypoxia and damage (e.g., involving the kidneys and/or liver).

The typical patient is anaemic but asymptomatic except during sickling episodes.

A broad range of symptoms can be seen in sickle cell disease, ranging from mild to severe in nature with infections.

Signs and Symptoms Related to PainSudden pain throughout the body is a common symptom of sickle cell anemia. This pain is called a "sickle cell crisis." Sickle cell crises often affect the bones, lungs, abdomen, and joints.

The pain from sickle cell crises can be acute or chronic, but acute pain is more common. Acute pain is sudden and can range from mild to very severe. The pain usually lasts from hours to a few days. Chronic pain often lasts for weeks to months. Chronic pain can be hard to bear and mentally draining. This pain may severely limit your daily activities.

Painful crises are the leading cause of emergency room visits and hospitalizations of people who have sickle cell anemia.

• The primary symptom associated with sickling is pain. During sickle cell crisis the pain is quite severe as a result of tissue ischemia. Sudden bursts of pain are also a common symptom; pain can be acute (short-lived) or chronic (long-lasting). Can have severe pain anywhere in the body. Symptoms vary in severity from person to person. Pain may be present in
  • the back,
  • chest (with difficulty in breathing)
  • extremities (arthritic)
  • abdomen (may be due to blockage of blood flow to spleen or liver)
  • Pain episodes are accompanied by
  • fever
  • swelling
  • tenderness
  • tachypnea
  • hypertension
  • nausea and vomiting.

Signs and Symptoms Related to Anaemia

The most common symptom of anaemia are

• Fatigue (feeling tired or weak)
• Paleness (pallor)
• Jaundice (may include gallstones)
• Blue skin
• Shortness of breath
• Dizziness
• Headache
• Coldness in the hands and feet
• Chest pain

Because most individuals with sickle cell anaemia have dark skin, pallor is more readily detected by examining the mucous membranes. The skin may have a greyish cast. Because of the hemolysis, jaundice is common and patients are prone to gallstones (cholelithiasis).

With repeated episodes of sickling, there is gradual involvement of all body systems, especially the spleen, lungs, kidneys, and brain.

• Infection is a major cause of morbidity and mortality in patients with sickle cell disease. Pneumonia is the most common infection.
• The spleen becomes infarcted, dysfunctional, and small because of repeated scarring.
• Acute chest syndrome describes pulmonary complications that include pneumonia, tissue infarction, and fat embolism, resulting in pulmonary hypertension, MI [heart attack], and ultimately cor pulmonale.
• The kidneys may be injured from the lack of oxygen, resulting in renal failure.
• Stroke can result from thrombosis and infarction of cerebral blood vessels.
• The heart may become ischemic and enlarged, leading to heart failure.
• Retinal vessel obstruction may result in hemorrhage, scarring, retinal detachment, and blindness.
• Bone changes may include osteoporosis and osteosclerosis after infarction. Chronic leg ulcers can result from hypoxia.

Answer 6

Some of the most common symptoms for sickle cell anemia are shortness of breath, dizziness, headaches, coldness in the hands and feet, paler than normal skin or mucous membranes, and jaundice.

Answer 7

ask your doctor and let him/she run some tests on you

Answer 8

Physical symptoms: fever, fatigue, weakness, dizziness, headache, pale skin, shortness of breath, cold hands and feet.

Answer 9

fatigue