the conversion of R forms of one type into S forms of a different type
the conversion of R forms of one type into S forms of a different type
The live R bacteria acquired a capsule and became live, virulent S bacteria.
The live R bacteria acquired a capsule and became live, virulent S bacteria.
Fred Griffith found that genetic information could be transferred between different strains of bacteria, specifically between the harmless R strain and the virulent S strain of bacteria. This led to the discovery of transformation, a process where genetic material is exchanged between bacteria.
The S bacteria are surrounded by a capsule, so it is not engulfed by the host's white blood cells. That means that it is able to proliferate and spread. The R bacteria lack the capsule (like the mutant S bacteria), so the white blood cells are able to detect and eliminate them.
R bacteria have a rough appearance due to the presence of a sugar capsule on their outer surface, making them resistant to the immune system. S bacteria are smooth in appearance and lack the protective capsule, making them vulnerable to the immune system. This difference in structure affects the virulence and pathogenicity of the bacteria.
The S bacteria possess a protective polysaccharide capsule that helps them evade the immune system, allowing them to survive and cause infection. The R bacteria lack this capsule and are easily targeted and eliminated by the immune system, thus they are not virulent.
The S form of bacteria typically causes disease, as it has a polysaccharide capsule that aids in virulence and evasion of the immune system. The R form does not have this capsule and is usually avirulent.
The S strain produces a capsule but the R strain does not
The molecule that caused transformation in Griffith's mouse experiment was DNA. When heat-killed S strain bacteria (which had DNA) were mixed with live R strain bacteria (which did not), the DNA from the dead S strain bacteria was able to transfer genetic information to the live R strain bacteria, making them pathogenic.
The process is called transformation, and it was the first direct evidence that genetic information could be transferred between bacteria. In Griffith's experiment, the heat-killed S strain released its genetic material, which was then taken up by the live R strain, converting it into the deadly S strain.
Griffith hypothesized that a chemical component from the virulent S cells had somehow transformed the R cells into the more virulent S form.